Introduction:Basic information about CAS 103429-31-8|H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 trifluoroacetate salt (Disulfide bond), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 trifluoroacetate salt (Disulfide bond) |
|---|
| CAS Number | 103429-31-8 | Molecular Weight | 1062.26000 |
|---|
| Density | 1.42g/cm3 | Boiling Point | 1491.2ºC at 760mmHg |
|---|
| Molecular Formula | C50H67N11O11S2 | Melting Point | / |
|---|
| MSDS | USA | Flash Point | 855.7ºC |
|---|
Names
| Name | ctop |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | CTOP is a peptide that acts as a μ-opioid receptor antagonist. |
|---|
| Related Catalog | Signaling Pathways >>GPCR/G Protein >>Opioid ReceptorSignaling Pathways >>Neuronal Signaling >>Opioid ReceptorResearch Areas >>Neurological Disease |
|---|
Chemical & Physical Properties
| Density | 1.42g/cm3 |
|---|
| Boiling Point | 1491.2ºC at 760mmHg |
|---|
| Molecular Formula | C50H67N11O11S2 |
|---|
| Molecular Weight | 1062.26000 |
|---|
| Flash Point | 855.7ºC |
|---|
| Exact Mass | 1061.45000 |
|---|
| PSA | 425.91000 |
|---|
| LogP | 3.30840 |
|---|
| Vapour Pressure | 0mmHg at 25°C |
|---|
| Index of Refraction | 1.68 |
|---|
| InChIKey | PZWWYAHWHHNCHO-UHFFFAOYSA-N |
|---|
| SMILES | CC(O)C(NC(=O)C1NC(=O)C(C(C)O)NC(=O)C(CCCN)NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(NC(=O)C(N)Cc2ccccc2)CSSC1(C)C)C(N)=O |
|---|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| WGK Germany | 3 |
|---|
Articles40
More Articles
| Activation of mu or delta opioid receptors in the lumbosacral spinal cord is essential for ejaculatory reflexes in male rats. PLoS ONE 10(3) , e0121130, (2015) Ejaculation is controlled by a spinal ejaculation generator located in the lumbosacral spinal cord, consisting in male rats of lumbar spinothalamic (LSt) cells and their inter-spinal projections to au... | |
| Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude. J. Neurosci. 35 , 9580-94, (2015) Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, des... | |
| Synaptic upregulation and superadditive interaction of dopamine D2- and μ-opioid receptors after peripheral nerve injury. Pain 155(12) , 2526-33, (2014) A sound strategy for improving the clinical efficacy of opioids involves exploiting positive interactions with drugs directed at other targets in pain pathways. The current study investigated the role... | |
Synonyms
| DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL |
| NTB |
| D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-amide |
| M.W. 1062.26 C50H67N11O11S2 |
| D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 |
| CYS2,TYR3,ORN5,PEN7-AMIDE |
| threoninamide |
| D-Phe-Cys-Tyr-D-Trp-Orn-Pen-Thr-NH2 |
| [Cys2, Tyr3, Orn5, Pen7]-Somatostatin 14 (7-14), amide |