Introduction：Basic information about CAS 153436-22-7|Gavestinel, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gavestinel |
|---|
| CAS Number | 153436-22-7 | Molecular Weight | 375.21 |
|---|
| Density | 1.561g/cm3 | Boiling Point | 701.1ºC at 760mmHg |
|---|
| Molecular Formula | C18H12Cl2N2O3 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 377.8ºC |
|---|
Names
| Name | 3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylic acid |
|---|
| Synonym | More Synonyms |
|---|
Gavestinel BiologicalActivity
| Description | Gavestinel (GV 150526) is a selective and potent the glycine site of the NMDA receptor antagonist. Gavestinel has neuroprotectant effects[1]. |
|---|
| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
|---|
| References | [1]. J F Hoke, et al. Pharmacokinetics of a glycine site antagonist (gavestinel) following multiple dosing in patients with acute stroke. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):867-72. |
|---|
Chemical & Physical Properties
| Density | 1.561g/cm3 |
|---|
| Boiling Point | 701.1ºC at 760mmHg |
|---|
| Molecular Formula | C18H12Cl2N2O3 |
|---|
| Molecular Weight | 375.21 |
|---|
| Flash Point | 377.8ºC |
|---|
| Exact Mass | 396.00400 |
|---|
| PSA | 85.02000 |
|---|
| LogP | 3.56310 |
|---|
| Vapour Pressure | 1.24E-20mmHg at 25°C |
|---|
| InChIKey | WZBNEZWCNKUOSM-VOTSOKGWSA-N |
|---|
| SMILES | O=C(C=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccccc1 |
|---|
Synonyms
