Introduction：Basic information about CAS 117928-94-6|GLYX 13 TFA, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | GLYX 13 TFA |
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| CAS Number | 117928-94-6 | Molecular Weight | 413.46900 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C18H31N5O6 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | GLYX-13 trifluoroacetate |
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| Synonym | More Synonyms |
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GLYX 13 TFA BiologicalActivity
| Description | Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. Target: NMDARapastinel is a robust cognitive enhancer and facilitates hippocampal long-term potentiation (LTP) of synaptic transmission in slices. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>iGluRSignaling Pathways >>Neuronal Signaling >>iGluRResearch Areas >>Neurological DiseasePeptides |
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| References | [1]. Burgdorf J, et al. The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus. Neuroscience. 2015 Nov 12;308:202-11. |
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Chemical & Physical Properties
| Molecular Formula | C18H31N5O6 |
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| Molecular Weight | 413.46900 |
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| Exact Mass | 413.22700 |
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| PSA | 179.29000 |
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| Storage condition | -20°C |
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Synonyms
| L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate |
| Thr-Pro-Pro-Thr-NH2 trifluoroacetate TPPT-amide trifluoroacetate |
| (2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide |
| Rapastinel |
| GLYX 13 |
