CAS 118506-26-6|Myelin Basic Protein (87-99) (human, bovine, rat)

Introduction：Basic information about CAS 118506-26-6|Myelin Basic Protein (87-99) (human, bovine, rat), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Myelin Basic Protein (87-99) (human, bovine, rat)
CAS Number	118506-26-6	Molecular Weight	1555.82000
Density	/	Boiling Point	/
Molecular Formula	C₇₄H₁₁₄N₂₀O₁₇	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Myelin Basic Protein (87-99)
Synonym	More Synonyms

BiologicalActivity

Description	Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References	[1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12. [2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.

Description

Myelin Basic Protein(87-99) is an encephalitogenic peptide that induces basic protein-specific T cell proliferation. Myelin Basic Protein(87-99) causes a Th1 polarization in peripheral blood mononuclear cells with is implicated of multiple sclerosis (MS)[1][2].

Related Catalog

Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology

References

[1]. R E Jones, et al. The synthetic 87-99 peptide of myelin basic protein is encephalitogenic in Buffalo rats. J Neuroimmunol. 1992 Apr;37(3):203-12.

[2]. George Deraos, et al. Citrullination of linear and cyclic altered peptide ligands from myelin basic protein (MBP(87-99)) epitope elicits a Th1 polarized response by T cells isolated from multiple sclerosis patients: implications in triggering disease. J Med Chem. 2008 Dec 25;51(24):7834-42.

Chemical & Physical Properties

Molecular Formula	C₇₄H₁₁₄N₂₀O₁₇
Molecular Weight	1555.82000
Exact Mass	1554.87000
PSA	595.09000
LogP	3.14350
InChIKey	XSSZRUKIAIQNAZ-UNBJHMBOSA-N
SMILES	CCC(C)C(NC(=O)C(CC(N)=O)NC(=O)C(CCCCN)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(N)C(C)C)C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)NC(C(=O)N1CCCC1C(=O)O)C(C)O)C(C)O)C(C)C

Synonyms

h-val-his-phe-phe-lys-asn-ile-val-thr-pro-arg-thr-pro-oh

val-his-phe-phe-lys-asn-ile-val-thr-pro-arg-thr-pro

vhffknivtprtp

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