CAS 181936-98-1|KC 12291 hydrochloride

Introduction：Basic information about CAS 181936-98-1|KC 12291 hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. KC 12291 hydrochloride BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	KC 12291 hydrochloride
CAS Number	181936-98-1	Molecular Weight	449.99
Density	/	Boiling Point	/
Molecular Formula	C₂₂H₂₈ClN₃O₃S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-3-[(5-phenyl-1,2,4-thiadiazol-3-yl)oxy]propan-1-amine,hydrochloride
Synonym	More Synonyms

KC 12291 hydrochloride BiologicalActivity

Description	KC 12291 hydrochloride is an orally active blocker of voltage-gated sodium channel (VGSC). KC 12291 hydrochloride reduces the amplitude of sustained Na+ current to exert antiischemic activity. KC 12291 hydrochloride has significant cardioprotective effect in vitro and in vivo[1].
Related Catalog	Signaling Pathways >>Membrane Transporter/Ion Channel >>Sodium ChannelResearch Areas >>Cardiovascular Disease
References	[1]. John GW, et al. KC 12291: an atypical sodium channel blocker with myocardial antiischemic properties. Cardiovasc Drug Rev. 2004 Spring;22(1):17-26.

Chemical & Physical Properties

Molecular Formula	C₂₂H₂₈ClN₃O₃S
Molecular Weight	449.99
Exact Mass	449.15400
PSA	84.95000
LogP	4.96770
InChIKey	KIJPRQYBNQKUAU-UHFFFAOYSA-N
SMILES	COc1ccc(CCN(C)CCCOc2nsc(-c3ccccc3)n2)cc1OC.Cl

Safety Information

HS Code	2934999090

Customs

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

Xamoterol hemifumarate

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