CAS 929-75-9|Amino-PEG3-C2-Amine
| Common Name | Amino-PEG3-C2-Amine | ||
|---|---|---|---|
| CAS Number | 929-75-9 | Molecular Weight | 192.256 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 291.1±25.0 °C at 760 mmHg |
| Molecular Formula | C8H20N2O3 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 131.8±16.8 °C |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 3,6,9-Trioxaundecane-1,11-Diamine |
|---|---|
| Synonym | More Synonyms |
Amino-PEG3-C2-Amine BiologicalActivity
| Description | Amino-PEG3-C2-Amine is a PEG-based (3 units) PROTAC linker can be used in the synthesis of PROTACs. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References | [1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 291.1±25.0 °C at 760 mmHg |
| Molecular Formula | C8H20N2O3 |
| Molecular Weight | 192.256 |
| Flash Point | 131.8±16.8 °C |
| Exact Mass | 192.147400 |
| PSA | 79.73000 |
| LogP | -1.94 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.462 |
| InChIKey | NIQFAJBKEHPUAM-UHFFFAOYSA-N |
| SMILES | NCCOCCOCCOCCN |
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H318-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R37/38;R41 |
| Safety Phrases | S26-S39 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2922199090 |
Customs
| HS Code | 2922199090 |
|---|---|
| Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles4
More Articles| Orthogonal, convergent syntheses of dendrimers based on melamine with one or two unique surface sites for manipulation. J. Am. Chem. Soc. 123 , 8914 - 8922 , (2001) An orthogonal, convergent route for the introduction of substoichiometric numbers of latent surface sites into dendrimers based on melamine is used to prepare targets that display one or two Boc-prote... | |
| Non-natural glycosphingolipids and structurally simpler analogues bind HIV-1 recombinant Gp120. Bioorg. Med. Chem. 10 , 625- 637, (2002) Interactions of recombinant gp120 (rgp120) with non-natural glycosphingolipids (GSLs) and structurally simpler analogues have been studied using a competitive adhesion assay. Conjugates of cellobiosyl... | |
| Recapitulation of in vivo-like paracrine signals of human mesenchymal stem cells for functional neuronal differentiation of human neural stem cells in a 3D microfluidic system. Biomaterials 63 , 177-88, (2015) Paracrine signals produced from stem cells influence tissue regeneration by inducing the differentiation of endogenous stem or progenitor cells. However, many recent studies that have investigated par... |
Synonyms
| EINECS 213-206-2 |
| 2,2'-[oxybis(ethane-2,1-diyloxy)]diethanamine |
| Ethanamine, 2,2'-[oxybis(2,1-ethanediyloxy)]bis- |
| 2,2'-[Oxybis(ethylenoxy)]diethylamine |
| 2,2'-[Oxybis(2,1-ethanediyloxy)]diethanamine |
| MFCD00628164 |
| 3,6,9-trioxaundecamethylenediamine |
