Introduction:Basic information about CAS 71973-79-0|Suc-Ala-Ala-Phe-AMC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Suc-Ala-Ala-Phe-AMC |
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| CAS Number | 71973-79-0 | Molecular Weight | 564.58600 |
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| Density | 1.331g/cm3 | Boiling Point | 1002.6ºC at 760 mmHg |
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| Molecular Formula | C29H32N4O8 | Melting Point | / |
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| MSDS | ChineseUSA | Flash Point | 560.2ºC |
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| Symbol | GHS07 | Signal Word | Warning |
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Names
| Name | 4-[[1-[[1-[[1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid |
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| Synonym | More Synonyms |
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Suc-Ala-Ala-Phe-AMC BiologicalActivity
| Description | Suc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays[1][2][3]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Farach HA Jr, et al. Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm. J Biol Chem. 1987 Apr 25;262(12):5483-7. [2]. Pinto MR, et al. Chymotrypsin-like enzymes are involved in sperm penetration through the vitelline coat of Ciona intestinalis egg. Mol Reprod Dev. 1990 Aug;26(4):319-23. [3]. Mumford RA, et al. A zinc metalloendopeptidase associated with dog pancreatic membranes. J Biol Chem. 1980 Mar 25;255(6):2227-30. |
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Chemical & Physical Properties
| Density | 1.331g/cm3 |
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| Boiling Point | 1002.6ºC at 760 mmHg |
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| Molecular Formula | C29H32N4O8 |
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| Molecular Weight | 564.58600 |
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| Flash Point | 560.2ºC |
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| Exact Mass | 564.22200 |
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| PSA | 183.91000 |
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| LogP | 2.88730 |
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| Index of Refraction | 1.607 |
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| InChIKey | HHPVJKZZYOXPLH-UHFFFAOYSA-N |
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| SMILES | Cc1cc(=O)oc2cc(NC(=O)C(Cc3ccccc3)NC(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)O)ccc12 |
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Safety Information
| Symbol | GHS07 |
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| Signal Word | Warning |
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| Hazard Statements | H315-H319-H335 |
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| Precautionary Statements | P261-P305 + P351 + P338 |
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| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
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| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | 26 |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| AMC084 |
| Suc-AAF-AMC |
| N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin |
| Suc-Ala-Ala-Phe-AMC |
| Suc-Ala-Ala-Phe-7-Amino-4-Methylcoumarin |
| MFCD00038448 |