CAS 71973-79-0|Suc-Ala-Ala-Phe-AMC

Introduction:Basic information about CAS 71973-79-0|Suc-Ala-Ala-Phe-AMC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSuc-Ala-Ala-Phe-AMC
CAS Number71973-79-0Molecular Weight564.58600
Density1.331g/cm3Boiling Point1002.6ºC at 760 mmHg
Molecular FormulaC29H32N4O8Melting Point/
MSDSChineseUSAFlash Point560.2ºC
Symbol
GHS07
Signal WordWarning

Names

Name4-[[1-[[1-[[1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
SynonymMore Synonyms

Suc-Ala-Ala-Phe-AMC BiologicalActivity

DescriptionSuc-Ala-Ala-Phe-AMC is a fluorogenic chymotrypsin substrate, can be hydrolyzed by endopeptidase. Suc-Ala-Ala-Phe-AMC has been used in both in vivo assays of the acrosome reaction and in vitro enzyme assays[1][2][3].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
References

[1]. Farach HA Jr, et al. Evidence for the involvement of metalloendoproteases in the acrosome reaction in sea urchin sperm. J Biol Chem. 1987 Apr 25;262(12):5483-7.

[2]. Pinto MR, et al. Chymotrypsin-like enzymes are involved in sperm penetration through the vitelline coat of Ciona intestinalis egg. Mol Reprod Dev. 1990 Aug;26(4):319-23.

[3]. Mumford RA, et al. A zinc metalloendopeptidase associated with dog pancreatic membranes. J Biol Chem. 1980 Mar 25;255(6):2227-30.

Chemical & Physical Properties

Density1.331g/cm3
Boiling Point1002.6ºC at 760 mmHg
Molecular FormulaC29H32N4O8
Molecular Weight564.58600
Flash Point560.2ºC
Exact Mass564.22200
PSA183.91000
LogP2.88730
Index of Refraction1.607
InChIKeyHHPVJKZZYOXPLH-UHFFFAOYSA-N
SMILESCc1cc(=O)oc2cc(NC(=O)C(Cc3ccccc3)NC(=O)C(C)NC(=O)C(C)NC(=O)CCC(=O)O)ccc12

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety Phrases26
RIDADRNONH for all modes of transport

Synonyms

AMC084
Suc-AAF-AMC
N-Succinyl-Ala-Ala-Phe-7-amido-4-methylcoumarin
Suc-Ala-Ala-Phe-AMC
Suc-Ala-Ala-Phe-7-Amino-4-Methylcoumarin
MFCD00038448
CAS 588668-97-7|Potassium 1,1,2,2,3,3-Hexafluoropropane-1,3-disulfonimide
CAS 303136-70-1|xylenol blue sodium salt indicator
Recommended......
TOP