CAS 77591-33-4|Thymosin beta 4 acetate

Introduction：Basic information about CAS 77591-33-4|Thymosin beta 4 acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Thymosin beta 4 acetate BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Thymosin beta 4 acetate
CAS Number	77591-33-4	Molecular Weight	4963.44000
Density	/	Boiling Point	/
Molecular Formula	C₂₁₂H₃₅₀N₅₆O₇₈S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	Thymosin beta 4 acetate
Synonym	More Synonyms

Thymosin beta 4 acetate BiologicalActivity

Description	Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence: Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser.
Related Catalog	Signaling Pathways >>Others >>OthersResearch Areas >>Cardiovascular DiseasePeptides
Target	Actin[1].
In Vitro	As indicated by the significant reduction in the binding offluorescent phalloidin to injected cells, it is clear that (Thymosin beta 4 can induce an extensive depolymerization of actin filaments[1]. Treatment with the exogenous Thymosin beta 4 peptide inhibits the proliferation and migration of activated HSCs and reduces liver fibrosis[2].
References	[1]. Sanders MC, et al. Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4678-82. [2]. Kim J et al. Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells. Vitam Horm. 2016;102:121-49.

Chemical & Physical Properties

Molecular Formula	C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight	4963.44000
Exact Mass	4960.49000
PSA	2245.98000
InChIKey	UGPMCIBIHRSCBV-UHFFFAOYSA-N
SMILES	CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CC(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CO)NC(C)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)O)C(C)CC)C(C)O)C(C)O)C(C)O
Storage condition	-20°C

Synonyms

Thymosin β4 acetate

Thymosin beta 4

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