Introduction：Basic information about CAS 34701-53-6|Incensole acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Incensole acetate |
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| CAS Number | 34701-53-6 | Molecular Weight | 348.519 |
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| Density | 1.0±0.1 g/cm3 | Boiling Point | 420.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C22H36O3 | Melting Point | / |
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| MSDS | / | Flash Point | 178.6±23.3 °C |
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Names
| Name | Incensole acetate |
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| Synonym | More Synonyms |
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Incensole acetate BiologicalActivity
| Description | Incensole acetate is a main constituent of Boswellia carterii resin, has neuroprotective effects against neuronal damage in traumatic and ischemic head injury. Incensole acetate reduces Aβ25–35-triggered apoptosis in hOBNSCs[1]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>Apoptosis |
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| In Vitro | Incensole acetate (100 μM; pre-treatment 4 hours) significantly ameliorates Aβ 25–35-induced cell death, a 48–52% decrease in cell viability at Aβ25–35 is restored to 85–89% upon pre-treatment with IA[1]. Incensole acetate (5-100 μM) pretreatment reverses increase in the mRNA and protein level of Bax, caspase 8, cyto c and decrease in the mRNA and protein level of Bcl2 induced by Aβ 25–35 in hOBNSCs[1]. Cell Viability Assay[1] Cell Line: Human olfactory bulb neural stem cells Concentration: 100 μM Incubation Time: Pre-treatment 4 hours Result: Increased hOBNSCs cell viability induced by Aβ 25-35. |
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| References | [1]. El-Magd MA, et al. Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells. Biomed Pharmacother. 2018 Sep;105:813-823. |
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Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 420.1±45.0 °C at 760 mmHg |
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| Molecular Formula | C22H36O3 |
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| Molecular Weight | 348.519 |
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| Flash Point | 178.6±23.3 °C |
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| Exact Mass | 348.266449 |
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| PSA | 35.53000 |
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| LogP | 6.83 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.499 |
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| InChIKey | HVBACKJYWZTKCA-URCOVRKQSA-N |
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| SMILES | CC(=O)OC1CCC(C)=CCCC(C)=CCC2(C(C)C)CCC1(C)O2 |
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| Storage condition | -20℃ |
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Synonyms
| 15-Oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol, 1,5,9-trimethyl-12-(1-methylethyl)-, acetate, (5Z,9Z)- |
| (5Z,9Z)-12-Isopropyl-1,5,9-trimethyl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-yl acetate |
| rel-(1R,2S,5E,9E,12S)-12-isopropyl-1,5,9-trimethyl-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-yl acetate |
| (1R,2S,5E,9E,12S)-rel-1,5,9-Trimethyl-12-(1-methylethyl)-15-oxabicyclo[10.2.1]pentadeca-5,9-dien-2-ol 2-acetate |
