Introduction：Basic information about CAS 489415-96-5|SBC-115076, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | SBC-115076 |
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| CAS Number | 489415-96-5 | Molecular Weight | 527.611 |
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| Density | 1.3±0.0 g/cm3 | Boiling Point | 754.2±0.0 °C at 760 mmHg |
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| Molecular Formula | C31H33N3O5 | Melting Point | / |
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| MSDS | / | Flash Point | 409.9±0.0 °C |
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Names
| Name | 1,5-Dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-2H-pyrrol-2-one |
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| Synonym | More Synonyms |
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SBC-115076 BiologicalActivity
| Description | SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases.Target: PCSK9in vivo: SBC-115076 lowers cholesterol levels in mice that are fed high fat diet. |
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| Related Catalog | Signaling Pathways >>Autophagy >>AutophagyResearch Areas >>Cardiovascular Disease |
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| References | [1]. Abdel-Meguid, et al. Anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases |
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Chemical & Physical Properties
| Density | 1.3±0.0 g/cm3 |
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| Boiling Point | 754.2±0.0 °C at 760 mmHg |
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| Molecular Formula | C31H33N3O5 |
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| Molecular Weight | 527.611 |
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| Flash Point | 409.9±0.0 °C |
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| Exact Mass | 527.242004 |
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| LogP | 3.47 |
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| Vapour Pressure | 0.0±0.0 mmHg at 25°C |
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| Index of Refraction | 1.624 |
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| InChIKey | VVYIXKBHQQSREP-UHFFFAOYSA-N |
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| SMILES | Cc1cc(C(O)=C2C(=O)C(=O)N(CCCN3CCOCC3)C2c2ccncc2)ccc1OCc1ccccc1 |
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| Storage condition | -20℃ |
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Synonyms
| 4-[4-(Benzyloxy)-3-methylbenzoyl]-3-hydroxy-1-[3-(morpholin-4-yl)propyl]-5-(pyridin-4-yl)-1,5-dihydro-2H-pyrrol-2-one |
| 2H-Pyrrol-2-one, 1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)- |
| 4-[4-(Benzyloxy)-3-methylbenzoyl]-3-hydroxy-1-[3-(4-morpholinyl)propyl]-5-(4-pyridinyl)-1,5-dihydro-2H-pyrrol-2-one |
| SBC-115076 |
