CAS 479200-82-3|Amino-PEG11-amine

Introduction：Basic information about CAS 479200-82-3|Amino-PEG11-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Amino-PEG11-amine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Amino-PEG11-amine
CAS Number	479200-82-3	Molecular Weight	544.677
Density	1.1±0.1 g/cm3	Boiling Point	591.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₄H₅₂N₂O₁₁	Melting Point	/
MSDS	/	Flash Point	299.9±22.4 °C

Names

Name	3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine
Synonym	More Synonyms

Amino-PEG11-amine BiologicalActivity

Description	Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References	[1]. Shan M, et al. Nonsteroidal bivalent estrogen ligands: an application of the bivalent concept to the estrogen receptor. ACS Chem Biol. 2013 Apr 19;8(4):707-15.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	591.2±45.0 °C at 760 mmHg
Molecular Formula	C₂₄H₅₂N₂O₁₁
Molecular Weight	544.677
Flash Point	299.9±22.4 °C
Exact Mass	544.357117
LogP	-4.81
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.468
InChIKey	TZQCFDTWLKAGLL-UHFFFAOYSA-N
SMILES	NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN
Storage condition	2-8°C

Synonyms

3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane-1,35-diamine

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