Introduction：Basic information about CAS 528-63-2|Galgravin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Galgravin |
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| CAS Number | 528-63-2 | Molecular Weight | 372.45500 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C22H28O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | galgravin |
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| Synonym | More Synonyms |
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Galgravin BiologicalActivity
| Description | Galgravin is an active compound in Nectandra megapotamica, with anti-inflammatory activity. Galgravin displays in vitro cytotoxic activity and induce apoptosis in leukemia cells[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Galgravin has cytotoxic activity against human leukemia tumor cells with an IC50 of 16.5 µg/mL[2]. |
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| References | [1]. da Silva Filho AA, et al. Evaluation of analgesic and anti-inflammatory activities of Nectandra megapotamica (Lauraceae) in mice and rats. J Pharm Pharmacol. 2004 Sep;56(9):1179-84. [2]. Ponci V, et al. Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells. Molecules. 2015 Jul 15;20(7):12757-68. |
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Chemical & Physical Properties
| Molecular Formula | C22H28O5 |
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| Molecular Weight | 372.45500 |
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| Exact Mass | 372.19400 |
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| PSA | 46.15000 |
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| LogP | 4.80580 |
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| InChIKey | JLJAVUZBHSLLJL-DQEHQXCCSA-N |
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| SMILES | COc1ccc(C2OC(c3ccc(OC)c(OC)c3)C(C)C2C)cc1OC |
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Synonyms
| Galgravin |
| r-2,c-5-Bis(3,4-dimethoxyphenyl)-t-3,t-4-dimethyl-tetrahydrofuran |
| 2r,5cBis-(3,4-dimethoxy-phenyl)-3t,4t-dimethyl-tetrahydro-furan |
| (2S,3S,4R,5R)-2,5-Bis-(3,4-dimethoxy-phenyl)-3,4-dimethyl-tetrahydro-furan |
