Introduction：Basic information about CAS 480-00-2|eleutherol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | eleutherol |
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| CAS Number | 480-00-2 | Molecular Weight | 244.24300 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H12O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | eleutherol |
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| Synonym | More Synonyms |
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eleutherol BiologicalActivity
| Description | Eleutherol is a naphthalene isolated from E. americana with antifungal activities[1]. Eleutherol is against yeasts Candida albicans, C. tropicalis, Saccharomyces cerevisiae and Cryptococcus neoformans with MIC values between 7.8 µg/mL and 250 µg/mL[1]. Eleutherol inhibits α-glucosidase function with an IC50>1.00 mM[2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| Target | MIC: antifungal[1] |
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| References | [1]. Adriana Campos, et al. Antifungal Activity of Pyranonaphthoquinones Obtained from Cipura paludosa Bulbs. Nat Prod Commun. 2015 Sep;10(9):1589-92. [2]. Tomohiro Ieyama,et al.α-Glucosidase inhibitors from the bulb of Eleutherine americana. Food Chem.2011 Sep 15;128(2):308-11. |
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Chemical & Physical Properties
| Molecular Formula | C14H12O4 |
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| Molecular Weight | 244.24300 |
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| Exact Mass | 244.07400 |
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| PSA | 55.76000 |
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| LogP | 2.78540 |
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| InChIKey | KNLHGXVYZRQSJZ-SSDOTTSWSA-N |
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| SMILES | COc1cccc2cc3c(c(O)c12)C(C)OC3=O |
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| Storage condition | -20°C |
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Synonyms
| (R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one |
| (3R)-4-hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-one |
| (3R)-4-Hydroxy-5-methoxy-3-methyl-3H-naphtho[2,3-c]furan-1-on |
