Introduction：Basic information about CAS 49870-84-0|Corydamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Corydamine |
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| CAS Number | 49870-84-0 | Molecular Weight | 350.36800 |
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| Density | 1.334±0.06 g/cm3 | Boiling Point | 545.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H18N2O4 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | corydamine |
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| Synonym | More Synonyms |
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Corydamine BiologicalActivity
| Description | Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Topoisomerase |
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| Target | Topoisomerase I Topoisomerase II |
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| References | [1]. Xuemei Deng, et al. Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. Eur J Med Chem. 2022 Jan 15;228:113985. |
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Chemical & Physical Properties
| Density | 1.334±0.06 g/cm3 |
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| Boiling Point | 545.0±50.0 °C at 760 mmHg |
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| Molecular Formula | C20H18N2O4 |
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| Molecular Weight | 350.36800 |
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| Exact Mass | 350.12700 |
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| PSA | 61.84000 |
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| LogP | 3.51200 |
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| InChIKey | VWHAIQHZMVRBJN-UHFFFAOYSA-N |
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| SMILES | CNCCc1cc2c(cc1-c1cc3ccc4c(c3cn1)OCO4)OCO2 |
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Synonyms
| [2-(6-[1,3]Dioxolo[4,5-h]isoquinolin-7-yl-benzo[1,3]dioxol-5-yl)-ethyl]-methyl-amine |
| [2-(6-[1,3]dioxolo[4,5-h]isoquinolin-7-yl-benzo[1,3]dioxol-5-yl)-ethyl]-methyl-amine |
| Corydamin |
| 2-[6-([1,3]dioxolo[4,5-h]isoquinolin-7-yl)-1,3-benzodioxol-5-yl]-N-methylethanamine |
