CAS 78919-28-5|Chicanine

Introduction：Basic information about CAS 78919-28-5|Chicanine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chicanine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	Chicanine
CAS Number	78919-28-5	Molecular Weight	342.386
Density	1.2±0.1 g/cm3	Boiling Point	483.8±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₅	Melting Point	/
MSDS	/	Flash Point	246.4±28.7 °C

Names

Name	(+)-chicanine
Synonym	More Synonyms

Chicanine BiologicalActivity

Description	Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity[1].
Related Catalog	Signaling Pathways >>NF-κB >>IKKSignaling Pathways >>MAPK/ERK Pathway >>p38 MAPKResearch Areas >>Inflammation/ImmunologySignaling Pathways >>MAPK/ERK Pathway >>ERKSignaling Pathways >>Stem Cell/Wnt >>ERK
References	[1]. Chicanine, et al. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014 Feb 5;724:168-74.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	483.8±45.0 °C at 760 mmHg
Molecular Formula	C₂₀H₂₂O₅
Molecular Weight	342.386
Flash Point	246.4±28.7 °C
Exact Mass	342.146729
PSA	57.15000
LogP	3.88
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.575
InChIKey	JPDORDSJPIKURD-OCBHBYCGSA-N
SMILES	COc1cc(C2OC(c3ccc4c(c3)OCO4)C(C)C2C)ccc1O

Synonyms

Phenol, 4-[(2S,3R,4S,5S)-5-(1,3-benzodioxol-5-yl)tetrahydro-3,4-dimethyl-2-furanyl]-2-methoxy-

4-[(2S,3R,4S,5S)-5-(1,3-Benzodioxol-5-yl)-3,4-dimethyltetrahydro-2-furanyl]-2-methoxyphenol

chicanine

4-((2S,3R,4S,5S)-5-Benzo[1,3]dioxol-5-yl-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenol

Chicanin

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