Introduction：Basic information about CAS 1807530-05-7|Hydroxy-PEG4-O-Boc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydroxy-PEG4-O-Boc |
|---|
| CAS Number | 1807530-05-7 | Molecular Weight | 352.421 |
|---|
| Density | 1.1±0.1 g/cm3 | Boiling Point | 432.4±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C16H32O8 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 142.6±20.8 °C |
|---|
Names
| Name | Hydroxy-PEG5-t-butyl acetate |
|---|
| Synonym | More Synonyms |
|---|
Hydroxy-PEG4-O-Boc BiologicalActivity
| Description | Hydroxy-PEG5-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
|---|
| Target | PEGs |
|---|
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
|---|
| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
|---|
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|
| Boiling Point | 432.4±40.0 °C at 760 mmHg |
|---|
| Molecular Formula | C16H32O8 |
|---|
| Molecular Weight | 352.421 |
|---|
| Flash Point | 142.6±20.8 °C |
|---|
| Exact Mass | 352.209717 |
|---|
| LogP | -0.60 |
|---|
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.454 |
|---|
| InChIKey | XPLBSNFHNMATJJ-UHFFFAOYSA-N |
|---|
| SMILES | CC(C)(C)OC(=O)COCCOCCOCCOCCOCCO |
|---|
Synonyms
| MFCD27977509 |
| 3,6,9,12,15-Pentaoxaheptadecan-1-oic acid, 17-hydroxy-, 1,1-dimethylethyl ester |
| 2-Methyl-2-propanyl 17-hydroxy-3,6,9,12,15-pentaoxaheptadecan-1-oate |
