CAS 474922-26-4|DSPE-PEG(2000)-Amine

Introduction：Basic information about CAS 474922-26-4|DSPE-PEG(2000)-Amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. DSPE-PEG(2000)-Amine BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	DSPE-PEG(2000)-Amine
CAS Number	474922-26-4	Molecular Weight	896.226
Density	/	Boiling Point	/
Molecular Formula	(C₂H₄O)nC₄₄H₈₇N₂O₁₀P_.NH₃	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	1,2-distearoyl-sn-glycero-3-phosphoethanolaMine-N-[aMino(polyethylene glycol)-2000] (aMMoniuM salt)
Synonym	More Synonyms

DSPE-PEG(2000)-Amine BiologicalActivity

Description	DSPE-PEG(2000)-Amine is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
In Vitro	DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability[3].
References	[1]. Feilong Sun, et al. A Mixed Micelle Formulation for Oral Delivery of Vitamin K. Pharm Res. 2016 Sep;33(9):2168-79. [2]. Brian R Sloat, et al. In Vitro and in Vivo Anti-Tumor Activities of a Gemcitabine Derivative Carried by Nanoparticles. Int J Pharm. 2011 May 16;409(1-2):278-88. [3]. Cangel Pui-yee Chan, et al. Nanocrystal Biolabels With Releasable Fluorophores for Immunoassays. Anal Chem. 2004 Jul 1;76(13):3638-45.

Chemical & Physical Properties

Molecular Formula	(C₂H₄O)nC₄₄H₈₇N₂O₁₀P_.NH₃
Molecular Weight	896.226
Exact Mass	895.662598
InChIKey	AXHRCGLQEUQOIS-UHFFFAOYSA-N
SMILES	CCCCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)OCCOCCN)OC(=O)CCCCCCCCCCCCCCCCC.N
Storage condition	-20°C

Safety Information

Hazard Class	6.1

Synonyms

Octadecanoic acid, 1-[[[[2-[[[2-(2-aminoethoxy)ethoxy]carbonyl]amino]ethoxy]hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, ammonium salt

35-Amino-24-hydroxy-24-oxido-18,29-dioxo-19,23,25,30,33-pentaoxa-28-aza-24λ5-phosphapentatriacontan-21-yl octadecanoate ammoniate (1:1)

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