CAS 928007-64-1|Skinasensyl

Introduction:Basic information about CAS 928007-64-1|Skinasensyl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameSkinasensyl
CAS Number928007-64-1Molecular Weight613.703
Density1.3±0.1 g/cm3Boiling Point1055.3±65.0 °C at 760 mmHg
Molecular FormulaC34H39N5O6Melting Point/
MSDS/Flash Point592.0±34.3 °C

Names

NameSkinasensyl
SynonymMore Synonyms

Skinasensyl BiologicalActivity

DescriptionAcetyl tetrapeptide-15 is a synthetic peptide used in the cosmetics for sensitive skin. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway[1].
Related CatalogSignaling Pathways >>GPCR/G Protein >>Opioid ReceptorSignaling Pathways >>Neuronal Signaling >>Opioid ReceptorResearch Areas >>Neurological Disease
References

[1]. Resende DISP, et al. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel). 2021;14(8):702.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point1055.3±65.0 °C at 760 mmHg
Molecular FormulaC34H39N5O6
Molecular Weight613.703
Flash Point592.0±34.3 °C
Exact Mass613.290039
LogP2.72
Vapour Pressure0.0±0.3 mmHg at 25°C
Index of Refraction1.617
InChIKeyBSXFOBDOGHFWOC-KRCBVYEFSA-N
SMILESCC(=O)NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O

Safety Information

Hazard CodesXi

Synonyms

N-Acetyl-L-tyrosyl-L-prolyl-L-phenylalanyl-L-phenylalaninamide
L-Phenylalaninamide, N-acetyl-L-tyrosyl-L-prolyl-L-phenylalanyl-
Acetyl tetrapeptide 15
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