Introduction：Basic information about CAS 1577222-14-0|Diroximel fumarate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Diroximel fumarate |
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| CAS Number | 1577222-14-0 | Molecular Weight | 255.224 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 441.0±25.0 °C at 760 mmHg |
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| Molecular Formula | C11H13NO6 | Melting Point | / |
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| MSDS | / | Flash Point | 220.5±23.2 °C |
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Names
| Name | Diroxamel fumarate |
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| Synonym | More Synonyms |
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Diroximel fumarate BiologicalActivity
| Description | Diroximel fumarate (DRF) is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Angela Wehr, et al. Relative Bioavailability of Monomethyl Fumarate after Administration of ALKS 8700 and Dimethyl Fumarate in Healthy Subjects (P1.403). Neurology. Apr 2018. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 441.0±25.0 °C at 760 mmHg |
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| Molecular Formula | C11H13NO6 |
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| Molecular Weight | 255.224 |
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| Flash Point | 220.5±23.2 °C |
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| Exact Mass | 255.074280 |
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| LogP | -0.24 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.515 |
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| InChIKey | YIMYDTCOUQIDMT-SNAWJCMRSA-N |
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| SMILES | COC(=O)C=CC(=O)OCCN1C(=O)CCC1=O |
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| Storage condition | -20℃ |
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Synonyms
| ALKS 8700 |
| 2-Butenedioic acid, 2-(2,5-dioxo-1-pyrrolidinyl)ethyl methyl ester, (2E)- |
| MFCD28502263 |
| 2-(2,5-Dioxo-1-pyrrolidinyl)ethyl methyl (2E)-2-butenedioate |
| Diroxamel fumarate |
| Diroximel fumarate |
| RDC-5108 |
