Introduction：Basic information about CAS 71183-66-9|DL-threo-2-methylisocitrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DL-threo-2-methylisocitrate |
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| CAS Number | 71183-66-9 | Molecular Weight | 412.30 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C14H20O14 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | DL-threo-2-methylisocitrate |
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DL-threo-2-methylisocitrate BiologicalActivity
| Description | DL-threo-2-methylisocitrate is a substrate of isocitrate lyase 1(ICL1).IC50 value:Target: The Km of purified recombinant ICL1 for threo-D(s)L(s)-isocitrate (ICA) was determined to be 188 μM using Michaelis-Menten non-linear least squares fit, with a kcat of 5.24 s-1. The Km for DL-threo-2-methylisocitrate (MICA) was approximately fourfold higher at 718 μM with a kcat of 1.25 s-1. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Infection |
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| References | [1]. Gould TA, et al. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Mol Microbiol. 2006 Aug;61(4):940-7. |
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Chemical & Physical Properties
| Molecular Formula | C14H20O14 |
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| Molecular Weight | 412.30 |
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| InChIKey | HHKPKXCSHMJWCF-WVBDSBKLSA-N |
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| SMILES | CC(O)(C(=O)O)C(CC(=O)O)C(=O)O |
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| Storage condition | 2-8℃ |
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