Introduction：Basic information about CAS 1800414-71-4|Azido-PEG11-amine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Azido-PEG11-amine |
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| CAS Number | 1800414-71-4 | Molecular Weight | 570.674 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C24H50N4O11 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Azido-PEG11-amine |
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| Synonym | More Synonyms |
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Azido-PEG11-amine BiologicalActivity
| Description | Azido-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Molecular Formula | C24H50N4O11 |
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| Molecular Weight | 570.674 |
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| Exact Mass | 570.347595 |
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| LogP | -3.95 |
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Synonyms
| 35-Azido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontan-1-amine |
| Azido-dPEG(R)11-amine |
| 3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontan-1-amine, 35-azido- |
| MFCD08274605 |
