Introduction：Basic information about CAS 82217-01-4|m-PEG8-Tos, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG8-Tos |
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| CAS Number | 82217-01-4 | Molecular Weight | 538.65 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C24H42O11S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
m-PEG8-Tos BiologicalActivity
| Description | Tos-PEG8-m is a derivative of silybin ethers, extracted from patent CN105037337A (compound III-d). Tos-PEG8-m is a PEG-based PROTAC linker can be used in the synthesis of Silymarin (HY-W043277)[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
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| References | [1]. Yuxia Zhao, et al. Derivative of silybin ethers, and synthetic method and application thereof. Patent CN105037337A. |
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Chemical & Physical Properties
| Molecular Formula | C24H42O11S |
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| Molecular Weight | 538.65 |
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| InChIKey | PAXJFLMMCORNQI-UHFFFAOYSA-N |
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| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOS(=O)(=O)c1ccc(C)cc1 |
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| Storage condition | 2-8°C |
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