Introduction：Basic information about CAS 189351-79-9|19,20-Epoxycytochalasin C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 19,20-Epoxycytochalasin C |
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| CAS Number | 189351-79-9 | Molecular Weight | 523.617 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 737.4±60.0 °C at 760 mmHg |
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| Molecular Formula | C30H37NO7 | Melting Point | / |
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| MSDS | / | Flash Point | 399.7±32.9 °C |
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Names
| Name | Epoxycytochalasin C, 19,20- |
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| Synonym | More Synonyms |
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19,20-Epoxycytochalasin C BiologicalActivity
| Description | 19,20-Epoxycytochalasin C, a cytochalasin, is a fungal metabolite from Nemania sp. 19,20-Epoxycytochalasin C shows potent in vitro antiplasmodial activity and phytotoxicity[1]. |
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| Related Catalog | Research Areas >>CancerResearch Areas >>Infection |
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| Target | Microbial Metabolite |
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| In Vitro | 19,20-Epoxycytochalasin C shows moderate toxicity to cell line SK-MEL with an IC50 of 8.02 µM[1]. |
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| In Vivo | Evaluation of in vivo antimalarial activity of 19,20-Epoxycytochalasin C in a mouse model at 100 mg/kg dose shows that this compound has weak suppressive antiplasmodial activity and is toxic to animals[1]. |
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| References | [1]. Mallika Kumarihamy, et al. Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf. Molecules. 2019 Feb 21;24(4):777. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 737.4±60.0 °C at 760 mmHg |
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| Molecular Formula | C30H37NO7 |
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| Molecular Weight | 523.617 |
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| Flash Point | 399.7±32.9 °C |
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| Exact Mass | 523.257019 |
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| LogP | 3.64 |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.610 |
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| InChIKey | ZOSGFLUFAVFHCM-WSRKEQNVSA-N |
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| SMILES | CC(=O)OC1C2OC2C(C)(O)C(=O)C(C)CC=CC2C(O)C(C)=C(C)C3C(Cc4ccccc4)NC(=O)C213 |
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Synonyms
| 19,20-Epoxycytochalasin C |
| 3H-Oxireno[9,10]cycloundec[1,2-d]isoindole-3,13(4H)-dione, 14-(acetyloxy)-1a,2,5,7a,8,10a,11,12,14,14a-decahydro-2,8-dihydroxy-2,4,9,10-tetramethyl-11-(phenylmethyl)-, (1aR,2R,4S,6E,7aR,8S,10aR,11S,13aR,14aS)- |
| (1aR,2R,4S,6E,7aR,8S,10aR,11S,13aR,14aS)-11-Benzyl-2,8-dihydroxy-2,4,9,10-tetramethyl-3,13-dioxo-2,3,4,5,7a,8,10a,11,12,13,14,14a-dodecahydro-1aH-oxireno[9,10]cycloundeca[1,2-d]isoindol-14-yl acetate |
