Introduction：Basic information about CAS 58479-71-3|5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine |
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| CAS Number | 58479-71-3 | Molecular Weight | 330.36 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C13H18N2O6S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | 5-HydroxyMethyl-2',3'-O-isopropylidene-2-thiouridine |
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BiologicalActivity
| Description | 5-Hydroxymethyl-2',3'-O-isopropylidene-2-thiouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog |
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| References | [1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. |
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Chemical & Physical Properties
| Molecular Formula | C13H18N2O6S |
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| Molecular Weight | 330.36 |
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| InChIKey | BETDENPMPLSMTA-TURQNECASA-N |
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| SMILES | CC1(C)OC2C(CO)OC(n3cc(CO)c(=O)[nH]c3=S)C2O1 |
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