CAS 65428-13-9|1-Methoxyphaseollidin

Introduction：Basic information about CAS 65428-13-9|1-Methoxyphaseollidin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 1-Methoxyphaseollidin BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	1-Methoxyphaseollidin
CAS Number	65428-13-9	Molecular Weight	354.39638
Density	1.3±0.1 g/cm3	Boiling Point	521.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₅	Melting Point	/
MSDS	/	Flash Point	269.3±30.1 °C

Names

Name	1-methoxyphaseollidin
Synonym	More Synonyms

1-Methoxyphaseollidin BiologicalActivity

Description	1-Methoxyphaseollidin, a flavonoid compound, is a lysoPAF acetyltransferase inhibitor, with an IC50 of 48 μM. 1-Methoxyphaseollidin exhibits anti-H.pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains[1][2][3].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
Target	Human Endogenous Metabolite
References	[1]. Fukai T, et, al. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sci. 2002 Aug 9;71(12):1449-63. [2]. Nagumo S, et, al. Inhibition of lysoPAF acetyltransferase activity by components of licorice root. Biol Pharm Bull. 1999 Oct;22(10):1144-6. [3]. Sinha SK, et, al. Potential Leads from Liquorice Against SARS-CoV-2 Main Protease using Molecular Docking Simulation Studies. Comb Chem High Throughput Screen. 2021;24(4):591-597.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	521.7±50.0 °C at 760 mmHg
Molecular Formula	C₂₁H₂₂O₅
Molecular Weight	354.39638
Flash Point	269.3±30.1 °C
Exact Mass	354.146729
LogP	4.32
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.621
InChIKey	YKTZRMXYANFKQR-YCRPNKLZSA-N
SMILES	COc1cc(O)cc2c1C1Oc3c(ccc(O)c3CC=C(C)C)C1CO2
Storage condition	2-8℃

Safety Information

Hazard Codes	Xi

Synonyms

EINECS 2017-001-1

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