Introduction：Basic information about CAS 71138-97-1|Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) |
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| CAS Number | 71138-97-1 | Molecular Weight | 286.28 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C10H22O9 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | HYDROXYPROPYL METHYL CELLULOSE ACETATE SUCCINATE |
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BiologicalActivity
| Description | Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility drugs. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD50 >2.5 g/kg[1]. |
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| Related Catalog | Research Areas >>Others |
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| In Vivo | Hydroxypropylmethyl cellulose acetate succinate（2.5 g/kg；p.o.；单剂量）在大鼠无显著急性毒性[1]。 Hydroxypropylmethyl cellulose acetate succinate（0.63、1.25、2.5 g/kg；p.o.；每日一次，连续 2 个月，每周 6 天）在大鼠无显著亚慢性毒性[1]。 Hydroxypropylmethyl cellulose acetate succinate（1.25 g/kg、2.5 g/kg；口服；每天一次，连续 2 个月，每周 6 天）在大鼠无显著慢性毒性[1]。 |
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| References | [1]. Hoshi N, et al. Toxicological studies of hydroxypropylmethylcellulose acetate succinate--acute toxicity in rats and rabbits, and subchronic and chronic toxicities in rats. J Toxicol Sci. 1985 Oct;10 Suppl 2:147-85. |
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Chemical & Physical Properties
| Molecular Formula | C10H22O9 |
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| Molecular Weight | 286.28 |
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| InChIKey | ZUAAPNNKRHMPKG-UHFFFAOYSA-N |
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| SMILES | CC(=O)O.CC(O)CO.CO.O=C(O)CCC(=O)O |
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