CAS 782475-35-8|Bromo-PEG3-Acid

Introduction:Basic information about CAS 782475-35-8|Bromo-PEG3-Acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBromo-PEG3-Acid
CAS Number782475-35-8Molecular Weight285.13228
Density/Boiling Point/
Molecular FormulaC9H17BrO5Melting Point/
MSDS/Flash Point/

Names

NameBromo-PEG3-Acid
SynonymMore Synonyms

Bromo-PEG3-Acid BiologicalActivity

DescriptionBromo-PEG3-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Molecular FormulaC9H17BrO5
Molecular Weight285.13228

Synonyms

Bromo-PEG3-C2-acid
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