Introduction：Basic information about (-)-PINORESINOL CAS 81446-29-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
(-)-PINORESINOL Basic information
| Product Name: | (-)-PINORESINOL |
| Synonyms: | (-)-PINORESINOL;Phenol, 4,4'-[(1R,3aS,4R,6aS)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis[2-methoxy-;4-[(3R,3aS,6R,6aS)-6-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol;()-Pinoresinol;(-)-Pinoresinol, 10 mM in DMSO |
| CAS: | 81446-29-9 |
| MF: | C20H22O6 |
| MW: | 358.39 |
| EINECS: | |
| Product Categories: | |
| Mol File: | Mol File |
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(-)-PINORESINOL Chemical Properties
| Melting point | 119-120 °C |
| Boiling point | 556.5±50.0 °C(Predicted) |
| density | 1.287±0.06 g/cm3(Predicted) |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 9.54±0.35(Predicted) |
Safety Information
(-)-PINORESINOL Usage And Synthesis
| Uses | (-)-Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-)-Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1]. |
| Definition | ChEBI: (-)-pinoresinol is an enantiomer of pinoresinol having (-)-1R,3aS,4R,6aS-configuration. It has a role as a plant metabolite. |
| target | TNF-α | COX | NF-kB | NOS | AP-1 | JNK | CDK | p21 |
| References | [1] Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29(1):139-46. DOI:10.1093/carcin/bgm255
[2] Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142(10):1798-805. DOI:10.3945/jn.112.162453 |
(-)-PINORESINOL Preparation Products And Raw materials
