(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone CAS 72332-33-3

Introduction：Basic information about (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone CAS 72332-33-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Basic information

• Product Name: (R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone
• Synonyms: (r*,s*)-(-)-8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinone;PROCATEROL;2(1h)-quinolinone,8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-,(r*,;8-hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1h)-quinolinone(r*,s;s*)-(+-)-;ent-Florfenicol AMine-d3;(S)-N,N-DiMethyl-3-(1-naphthalenyl-d7-oxy)-3-(2-thienyl)propanaMine;ANTI-SARS VIRUS SM antibody produced in rabbit
• CAS: 72332-33-3
• MF: C16H22N2O3
• MW: 290.36
• EINECS: 276-590-0
• Mol File: 72332-33-3.mol

(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Chemical Properties

• Melting point: 107-109°C
• storage temp.: -20°C
• solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol
• form: Solid
• color: White to Off-White
• biological source: rabbit
• CAS DataBase Reference: 72332-33-3(CAS DataBase Reference)

Safety Information

• Storage Class: 10 - Combustible liquids

(R*,S*)-(-)-8-Hydroxy-5-(1-hydroxy-2-((1-methylethyl)amino)butyl)-2(1H)-quinolinone Usage And Synthesis

Description

Like pirbuterol, procaterol exhibits similar broncholytic properties as albuteral, but it hassomewhat of a more prolonged action. It is recommended for use as an inhaled drug fortreating bronchial asthma.

Chemical Properties

Off-White Solid

Uses

A labelled intermediate of the enantiomer of Florfenicol (F405750), an antibacterial agent.

Definition

ChEBI: 8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one is a member of quinolines.

Brand name

Pro-Air (Parke-Davis).

Synthesis

Procaterol, 5-[1-hydroxy-2-[(1-methylethyl)amino]butyl]-8-hydroxy-2-(1H)quinolone (23.3.25), is synthesized by acylation of 8-hydroxy-2(1H)-quinolone with 2-bromobutyric acid chloride at the fifth position of the quinoline system, which gives thecompound 23.3.23. This undergoes action of isopropylamine, forming an aminoketone23.3.24, the carbonyl group of which is reduced by sodium borohydride, giving procaterol(23.3.25) .