Introduction：Basic information about (R,R)-1,2,4,5-Diepoxypentane CAS 109905-51-3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Table of Contents
- 1. (R,R)-1,2,4,5-Diepoxypentane Basic information
- 2. (R,R)-1,2,4,5-Diepoxypentane Chemical Properties
- 3. Safety Information
- 4. (R,R)-1,2,4,5-Diepoxypentane Usage And Synthesis
- 5. (R,R)-1,2,4,5-Diepoxypentane Preparation Products And Raw materials
(R,R)-1,2,4,5-Diepoxypentane Basic information
| Product Name: | (R,R)-1,2,4,5-Diepoxypentane |
| Synonyms: | (R,R)-1,2,4,5-Diepoxypentane |
| CAS: | 109905-51-3 |
| MF: | C5H8O2 |
| MW: | 100.11582 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 109905-51-3.mol |
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(R,R)-1,2,4,5-Diepoxypentane Chemical Properties
Safety Information
(R,R)-1,2,4,5-Diepoxypentane Usage And Synthesis
| Synthesis | The original procedure utilizes a reversible acyl transfer reaction of acetylacetone (1) using aluminum trichloride and chloroacetyl chloride. The reaction is driven forward through removal of acetyl chloride by distillation and the resulting dichlorodione is isolated (57–58% yield) as copper complex 2. The dione is then liberated from the metal under acidic conditions and subjected to Noyori asymmetric hydrogenation5–9 under high pressure to give dichlorodiol R,R-3 in 40% yield after recrystallization, which undergoes double cyclization under basic conditions to form bis-epoxide R,R-4 (92% yield; >97% ee).
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(R,R)-1,2,4,5-Diepoxypentane Preparation Products And Raw materials
| Raw materials | 2,4-Pentanediol, 1,5-dichloro-, (2S,4S)- |
