(R,R)-2,3-Butanediol CAS 24347-58-8

Introduction：Basic information about (R,R)-2,3-Butanediol CAS 24347-58-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(R,R)-2,3-Butanediol Basic information

• Product Name: (R,R)-2,3-Butanediol
• Synonyms: (2R,3R)-(-)-2,3-Butanediol, 99+% ee, 98+%;(2R,3R)-(-)-2,3-Butanediol, 99+% ee, 98+% 1GR;(R,R)-(-)-2,3-Butylene Glycol(R,R)-(-)-2,3-Dihydroxybutane;(R,R)-(-)-2,3-BUTANEDIOL FOR SYNTHESIS;(2R,3R)-2,3-Dihydroxybutane;2,3-Butanediol,(2R,3R)-;(2R,3R)-(-)-2,3-Butanediol 97%;levo-2,3-Butanediol
• CAS: 24347-58-8
• MF: C4H10O2
• MW: 90.12
• EINECS: 246-186-9
• Product Categories: Polyols;Enantiomer Excess & Absolute Configuration Determination;Simple Alcohols (Chiral);Synthetic Organic Chemistry;Chiral Compound;Chiral Building Blocks;Organic Building Blocks;Analytical Chemistry;Chiral Building Blocks;e.e. / Absolute Configuration Determination (NMR);Chiral Compounds;Diols
• Mol File: 24347-58-8.mol

(R,R)-2,3-Butanediol Chemical Properties

• Melting point: 16 °C
• Boiling point: 77.3-77.4 °C/10 mmHg (lit.)
• alpha: -13 º (neat)
• density: 0.987 g/mL at 25 °C (lit.)
• vapor pressure: 82.8Pa at 25℃
• refractive index: n20/D 1.433
• Fp: 185 °F
• storage temp.: Sealed in dry,Store in freezer, under -20°C
• form: Liquid
• pka: 14.67±0.20(Predicted)
• color: Clear colorless
• Optical Rotation: [α]23/D 13.2°, neat
• Water Solubility: soluble
• Sensitive: Hygroscopic
• Merck: 14,1568
• BRN: 4290593
• Stability: Stable. Hygroscopic, air sensitive. Incompatible with strong oxidizing agents, acid anhydrides, acid chlorides, chloroformates, reducing agents. Combustible.
• Cosmetics Ingredients Functions: SOLVENT FRAGRANCE HUMECTANT SKIN CONDITIONING
• InChI: 1S/C4H10O2/c1-3(5)4(2)6/h3-6H,1-2H3/t3-,4-/m1/s1
• InChIKey: OWBTYPJTUOEWEK-QWWZWVQMSA-N
• SMILES: C[C@@H](O)[C@@H](C)O
• LogP: -0.72 at 22℃
• CAS DataBase Reference: 24347-58-8(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Butanediol, [R-(R*,R*)]-(24347-58-8)

Safety Information

• Hazard Codes: Xi
• Safety Statements: 24/25
• RIDADR: NA1993
• WGK Germany: 3
• F: 3-10
• HazardClass: CBL
• HS Code: 29053980
• Storage Class: 10 - Combustible liquids

(R,R)-2,3-Butanediol Usage And Synthesis

Chemical Properties

colourless or slightly brown liquid

Uses

(2R,3R)-(-)-2,3-Butanediol is used as a chiral auxiliary, chiral ligand and building block. Cyclocondenses with ketones for (13)C NMR determination of optical purity. It is used in the resolution of carbonyl compounds in gas chromatography.

Uses

C₂ symmetric chiral diol with versatile applications as a chiral auxiliary, building block, and chiral ligand. Cyclocondenses with ketones for ¹³C NMR determination of optical purity.

Definition

ChEBI: The (R,R) diastereoisomer of butane-2,3-diol.

General Description

(2R,3R)-(-)-2,3-Butanediol is a key building block in pharmaceutical industry.

Flammability and Explosibility

Not classified

Purification Methods

Purify it by fractional distillation. The bis-(4-nitrobenzoate) has m 141-142o and [] (-) or (+) 52o (c 4 CHCl3). [Ghirardelli & Lucas J Am Chem Soc 79 734 1957, Rubin et al. J Am Chem Soc 74 425 1952, Neish Can J Res 27 6 1949, Neish & Ledingham Can J Res 27 694 1949, Beilstein 1 IV 2524-2525.]