(S)-(-)-4-Amino-2-hydroxybutyric acid CAS 40371-51-5

Introduction:Basic information about (S)-(-)-4-Amino-2-hydroxybutyric acid CAS 40371-51-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

(S)-(-)-4-Amino-2-hydroxybutyric acid Basic information

Product Name:(S)-(-)-4-Amino-2-hydroxybutyric acid
Synonyms:L-(-)-ALPHA-HYDROXY-GAMMA-AMINOBUTYRIC ACID;(S)-4-AMINO-2-HYDROXYBUTANOIC ACID;(S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID;(S)-4-AMINO-2-HYDROXYBUTYRIC ACID;L-(-)-alpha-hydroxy-γ-amino butyric acid(HABA);(R)-(-)-4-Amino-2-hydroxybutyricacid;(S)-(-)-4-AMINO-2-HYDROXYBUTYRIC ACID, 9 6%;(S)-(-)-AMINO-2-HYDROXYBUTYRIC ACID
CAS:40371-51-5
MF:C4H9NO3
MW:119.12
EINECS:
Product Categories:Carboxylic Acids;Chiral Building Blocks;Organic Building Blocks;chiral;API intermediates
Mol File:40371-51-5.mol

(S)-(-)-4-Amino-2-hydroxybutyric acid Chemical Properties

Melting point 200-203 °C (lit.)
alpha -30 º (c=1, water)
Boiling point 222.38°C (rough estimate)
density 1.3126 (rough estimate)
refractive index -30 ° (C=1, H2O)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Methanol (Very Slightly, Heated), Water
pka3.47±0.10(Predicted)
form Crystalline Powder, Crystals and/or Chunks
color White to beige
Optical Rotation[α]23/D 30°, c = 1 in H2O
Water Solubility almost transparency
Sensitive Hygroscopic
Stability:Hygroscopic
InChI1S/C4H9NO3/c5-2-1-3(6)4(7)8/h3,6H,1-2,5H2,(H,7,8)/t3-/m0/s1
InChIKeyIVUOMFWNDGNLBJ-VKHMYHEASA-N
SMILESNCC[C@H](O)C(O)=O
CAS DataBase Reference40371-51-5(CAS DataBase Reference)

Safety Information

Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26
WGK Germany 3
HS Code 29225090
Storage Class11 - Combustible Solids

(S)-(-)-4-Amino-2-hydroxybutyric acid Usage And Synthesis

Chemical Propertieswhite to light yellow crystal powder
Uses(S)-(-)-4-Amino-2-hydroxybutyric Acid is an analogue of γ-aminobutyric acid (GABA) with potential inhibitory activity on GABA binding and uptake by brain. Injection of (S)-(-)-4-Amino-2-hydroxybutyric Acid showed no significant changes in plasma growth hormone (GH) in healthy patients but increased plasma GH, prolactin, and cortisol levels in cerebrovascular patients.
Uses(S)-(-)-4-Amino-2-hydroxybutyric acid may be used in the preparation of 6′-amino-1-N-[(S)-4-amino-2-hydroxybutyryl]-6′-deoxylividomycin A.
General Description(S)-(-)-4-Amino-2-hydroxybutyric acid is an important moiety of butirosin, an aminoglycoside antibiotic.

(S)-(-)-4-Amino-2-hydroxybutyric acid Preparation Products And Raw materials

(S)-(-)-2-ACETOXYPROPIONYL CHLORIDE CAS 36394-75-9
(S)-(-)-ALPHA,ALPHA-DI(2-NAPHTHYL)-2-PYRROLIDINEMETHANOL CAS 127986-84-9
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