1,1'-Bis(di-tert-butylphosphino)ferrocene CAS 84680-95-5

Introduction：Basic information about 1,1'-Bis(di-tert-butylphosphino)ferrocene CAS 84680-95-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

1,1'-Bis(di-tert-butylphosphino)ferrocene Basic information

• Product Name: 1,1'-Bis(di-tert-butylphosphino)ferrocene
• Synonyms: BIS[(DI-TERT-BUTYLPHOSPHINO)CYCLOPENTADIENYL]IRON;1,1'-Bis(di-t-butylphosphino)ferrocene,min.98%;1,1'-Bis(di-tert-butylphosphino)ferrocene,min. 98%;1,1'-Bis(di-tert-butylphosphino)ferrocene ,98%;1,1'-Bis(di-tert-butylphosphin;98% DtBPF;1,1'-Bis(di-tert-butylphosphiNA)ferrocene;1,1'-Bis(di-t-butylphosphino)ferrocene, min. 98%
• CAS: 84680-95-5
• MF: C26H44FeP210*
• MW: 474.42
• EINECS: 626-167-5
• Product Categories: Achiral Phosphine;Aryl Phosphine;Classes of Metal Compounds;Fe (Iron) Compounds;Ferrocenes;Metallocenes;Phosphine Ligands;Synthetic Organic Chemistry;Transition Metal Compounds;Catalysis and Inorganic Chemistry;Phosphorus Compounds;Polydentate Phosphine Ligands
• Mol File: 84680-95-5.mol

1,1'-Bis(di-tert-butylphosphino)ferrocene Chemical Properties

• Melting point: 181-182°C (dec.)
• storage temp.: Inert atmosphere,Room Temperature
• form: crystal
• color: orange to red
• Water Solubility: Insoluble in water.
• InChI: InChI=1S/2C13H22P.Fe/c2*1-12(2,3)14(13(4,5)6)11-9-7-8-10-11;/h2*7-10H,1-6H3;
• InChIKey: FPLSJBJGQLJLSV-UHFFFAOYSA-N
• SMILES: P(C(C)(C)C)(C(C)(C)C)[C]1[CH][CH][CH][CH]1.P(C(C)(C)C)(C(C)(C)C)[C]1[CH][CH][CH][CH]1.[Fe] |^1:9,10,11,12,13,23,24,25,26,27|

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 22-24/25-36/37/39-26
• WGK Germany: 3
• TSCA: No
• HS Code: 29319090
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

1,1'-Bis(di-tert-butylphosphino)ferrocene Usage And Synthesis

Reaction

1. Ligand for synthesis of polycyclic indoles via Pd-catalyzed intramolecular heteroannulation.
2. Ligand for the palladium-catalyzed intramolecular arylation of aryl bromides under mild conditions.
3. Ligand for cross-coupling reactions between bromoarenes and potassium allyltrifluoroborates promoted by a catalyst prepared from Pd(OAc)2 and DTBPF selectively providing γ-coupling products.
4. Ligand for the copper-catalyzed system for the ß-boration of of a variety of α,ß-unsaturated amides.
5. Ligand for the synthesis of Paucifloral F and related indanone analogues via palladium-catalyzed α-arylation.
6. Ligand for the Pd-carbon monoxide complex catalyzed hydroxycarbonylation of aryl halides.
7. Ligand for the palladium-catalyzed β-C-glycosylation by decarboxylative allylation to normal pyran systems,and cis-2,6-disubstituted tetrahydropyrans.
8. Pd-catalyzed dearomative indole bisfunctionalization via a diastereoselective arylcyanation.
9. Ligand for the copper- DTBPF catalyzed C–H activation and carboxylation of terminal alkynes.

Chemical Properties

1,1'-Bis(di-tert-butylphosphino)ferrocene has good stability and reactivity and can participate in a variety of organometallic catalytic reactions, such as diene complex formation, carbonyl insertion, addition, reduction and deoxygenation reactions.

Uses

1,1'-BIS(DI-TERT-BUTYLPHOSPHINO)FERROCENE is an organophosphine compound and can be used as an organometallic ligand.

Uses

The rate of palladium-catalyzed amination of unactivated aryl chlorides is accelerated by sterically hindered chelating alkyl phosphines, ie, 1,1'-bis(di-tert-butylphosphino)ferrocene.

reaction suitability

reaction type: Cross Couplings
reagent type: ligand
reaction type: Arylations
reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction
reagent type: ligand
reaction type: Indole Forming Reactions
reagent type: ligand
reaction type: Suzuki-Miyaura Coupling

1,1'-Bis(di-tert-butylphosphino)ferrocene Preparation Products And Raw materials

• Raw materials: Ethyl acetate-->Tetrahydrofuran-->Dichloromethane-->n-Butyllithium-->Hexane-->Magnesium-->Phosphorus trichloride-->N,N,N',N'-Tetramethylethylenediamine-->2-Chloro-2-methylpropane-->Ferrocene-->Cinchonidine-->Di-tert-butylchlorophosphane-->2-Butanol-->Bromocyclohexane-->2,2'-Bipyridine