Introduction：Basic information about 17-OCTADECYNOIC ACID CAS 34450-18-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
17-OCTADECYNOIC ACID Basic information
| Product Name: | 17-OCTADECYNOIC ACID |
| Synonyms: | 17-ODA;17-ODYA;17-OCTADECYNOIC ACID;ODYA;17-OCTADECYNOIC ACID \ CYTOCHROME P450 E;17-ODYA (17-Octadecynoic acid);Alkynyl Stearic Acid;DZIILFGADWDKMF-UHFFFAOYSA-N |
| CAS: | 34450-18-5 |
| MF: | C18H32O2 |
| MW: | 280.45 |
| EINECS: | |
| Product Categories: | Cytochrome P450Enzyme Inhibitors by Enzyme;Cytochrome P450Unsaturated fatty acids and derivatives;A to;Arachidonic Acid Cascade;Enzyme Inhibitors;Monoenoic fatty acids;Others |
| Mol File: | 34450-18-5.mol |
|
17-OCTADECYNOIC ACID Chemical Properties
| Boiling point | 400.8±18.0 °C(Predicted) |
| density | 0.922±0.06 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | Soluble to 50 mM in ethanol and to 100 mM in DMSO |
| form | White solid. |
| pka | 4.78±0.10(Predicted) |
| color | White to off-white |
| InChI | 1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20) |
| InChIKey | DZIILFGADWDKMF-UHFFFAOYSA-N |
| SMILES | C#CCCCCCCCCCCCCCCCC(O)=O |
| CAS DataBase Reference | 34450-18-5(CAS DataBase Reference) |
Safety Information
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 |
17-OCTADECYNOIC ACID Usage And Synthesis
| Description | Alkynyl stearic acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry. |
| Uses | 17-ODYA (17-Octadecynoic acid) is a potent suicide inhibitor of LTB4 ω-oxidase. |
| Definition | ChEBI: Octadec-17-ynoic acid is an acetylenic fatty acid that is octadecanoi acid (stearic acid) which has been doubly dehydrogenated at positions 17 and 18 to give the corresponding alkynoic acid. It has a role as a P450 inhibitor, an EC 1.14.14.94 (leukotriene-B4 20-monooxygenase) inhibitor and an EC 1.14.15.3 (alkane 1-monooxygenase) inhibitor. It is a long-chain fatty acid, an acetylenic fatty acid, a terminal acetylenic compound and a monounsaturated fatty acid. |
| Biological Activity | Potent suicide inhibitor of LTB 4 ω -hydroxylase. |
| Biochem/physiol Actions | 17-Octadecynoic acid (7-ODYA) is an irreversible inhibitor of cytochrome P450 isozymes, that participates in long-chain fatty acid metabolism. |
| storage | Store at -20°C |
17-OCTADECYNOIC ACID Preparation Products And Raw materials
