Introduction：Basic information about 1-PHENYLSEMICARBAZIDE CAS 103-03-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
1-PHENYLSEMICARBAZIDE Basic information
| Product Name: | 1-PHENYLSEMICARBAZIDE |
| Synonyms: | 1-Phenylsemicarbazide,99%;1-PhenylseMicarbazide, 99% 25GR;1-Phenylsemicarbazide 99%;1-Phenylsemicarbazide hydrochloride;cryogenine(pharmaceutical);Febrimin;Fenylsemikarbazid;Hydrazine, 1-carbamoyl-2-phenyl- |
| CAS: | 103-03-7 |
| MF: | C7H9N3O |
| MW: | 151.17 |
| EINECS: | 203-072-3 |
| Product Categories: | Carbonyl Compounds;Organic Building Blocks;Ureas |
| Mol File: | 103-03-7.mol |
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1-PHENYLSEMICARBAZIDE Chemical Properties
| Melting point | 171-174 °C (lit.) |
| Boiling point | 273.17°C (rough estimate) |
| density | 1.2100 (rough estimate) |
| refractive index | 1.5860 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | acetone: very soluble(lit.) |
| pka | 11.16±0.43(Predicted) |
| form | powder to crystal |
| color | White to Light yellow |
| BRN | 743311 |
| InChI | 1S/C7H9N3O/c8-7(11)10-9-6-4-2-1-3-5-6/h1-5,9H,(H3,8,10,11) |
| InChIKey | AVKHCKXGKPAGEI-UHFFFAOYSA-N |
| SMILES | NC(=O)NNc1ccccc1 |
| CAS DataBase Reference | 103-03-7(CAS DataBase Reference) |
| IARC | 3 (Vol. 12, Sup 7) 1987 |
| EPA Substance Registry System | Phenicarbazide (103-03-7) |
Safety Information
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 45-36/37/39-26 |
| WGK Germany | 3 |
| RTECS | FD0575000 |
| TSCA | TSCA listed |
| HS Code | 29280090 |
| Storage Class | 11 - Combustible Solids |
1-PHENYLSEMICARBAZIDE Usage And Synthesis
| Uses | 1-Phenylsemicarbazide was used in the synthesis of a series of alkyl(aryl/heteroaryl) substituted 3-trifluoromethyl-1H-1-phenylpyrazoles and alkyl 3-carboxylate analogs by the cyclocondensation reactions with 4-alkoxy-1,1,1-trihaloalk-3-en-2-ones. |
| Definition | ChEBI: Phenicarbazide is a member of phenylhydrazines. |
| Brand name | Antipyretic dellepsoids d26. |
| World Health Organization (WHO) | Phenicarbazide, which has analgesic and antipyretic activity, wasintroduced in the 1970s. It has been withdrawn in at least one country on groundsof its adverse effect profile and it appears to have fallen into disuse in others. |
| Purification Methods | Crystallise it from water and dry it in a vacuum over KOH. [Beilstein 15 H 287, 15 II 106, 15 III 184, 15 IV 180.] |
1-PHENYLSEMICARBAZIDE Preparation Products And Raw materials
| Raw materials | Urea-->NITROSOPHENYLUREA-->Hydrazinecarboxamide, 2-(1-methylethylidene)-1-phenyl--->ethyl cyanate-->1,5-Diphenylcarbazide-->3,5-DIMETHYLPYRAZOLE-1-CARBOXAMIDE-->4-Fluorobenzhydrazide-->Urethane-->Phenylhydrazine hydrochloride-->PHENYLURETHANE-->1-Methyl-1-nitrosourea-->Phenylhydrazine |
| Preparation Products | Triazophos-->3-Hydroxy-1-phenyl-1,2,4-triazole |
