2,3-DIFLUORO-6-NITROPHENOL CAS 82419-26-9
Introduction：Basic information about 2,3-DIFLUORO-6-NITROPHENOL CAS 82419-26-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,3-DIFLUORO-6-NITROPHENOL Basic information
| Product Name: | 2,3-DIFLUORO-6-NITROPHENOL |
| Synonyms: | 2,3-DIFLUORO-6-NITROPHENOL;2-HYDROXY-3,4-DIFLUORO NITROBENZENE;6-NITRO-2,3-DIFLUOROPHENOL;2,3-Difluoro-6-Nitrophenol98%;2,3-Difluoro-6-nitrophenol, 97+%;Difluoro-6-nitrophenol;2,3-Difluoro-6-nitrophenol 97%;2,3-Didluoro-6-nitrophenol |
| CAS: | 82419-26-9 |
| MF: | C6H3F2NO3 |
| MW: | 175.09 |
| EINECS: | |
| Product Categories: | Oxygen Compounds;Phenols;Aromatic Phenols;Benzene series;Phenol&Thiophenol&Mercaptan;Organic Building Blocks |
| Mol File: | 82419-26-9.mol |
2,3-DIFLUORO-6-NITROPHENOL Chemical Properties
| Melting point | 60-62 °C (lit.) |
| Boiling point | 215.9±35.0 °C(Predicted) |
| density | 1.5200 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder to crystal |
| pka | 4.77±0.37(Predicted) |
| color | White to Light yellow to Green |
| BRN | 4410368 |
| InChI | 1S/C6H3F2NO3/c7-3-1-2-4(9(11)12)6(10)5(3)8/h1-2,10H |
| InChIKey | KEGOHDCHURMFKX-UHFFFAOYSA-N |
| SMILES | Oc1c(F)c(F)ccc1[N+]([O-])=O |
| CAS DataBase Reference | 82419-26-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xn,T,Xi |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36-36/37/39 |
| WGK Germany | 3 |
| Hazard Note | Toxic |
| HazardClass | IRRITANT, IRRITANT-HARMFUL |
| HS Code | 29089990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
| Chemical Properties | yellow crystals |
| Uses | 2,3-Difluoro-6-nitrophenol was used in the synthesis of 2-methyl-6,7-difluoro-8-oxyquinoline. |
| Synthesis | 771-69-7 82419-26-9 a. Add 45.2 g of 2,3,4-trifluoronitrobenzene and 99.5 g of dimethyl sulfoxide (DMSO) to a 1000 mL three-necked flask and stir until completely dissolved. b. Adjust the temperature of the reaction system to 15~17°C, slowly add 125 g of 32% potassium hydroxide (KOH) solution dropwise, and strictly control the temperature during the dropwise addition process. c. Continue to stir the reaction for 3 hours at 15~17°C. d. Upon completion of the reaction, cool the reaction system to 14~16°C, slowly add 290 g of 7.6% potassium hydroxide. e. Add 290 g of 7.6% hydrochloric acid, and slowly add 290 g of 7.6% hydrochloric acid, and stir for 3 hours. -nitrophenol. |
| References | [1] Patent: US5292967, 1994, A [2] Chemical and Pharmaceutical Bulletin, 1984, vol. 32, # 12, p. 4907 - 4913 [3] Patent: US4382892, 1983, A [4] Patent: CN106632444, 2017, A. Location in patent: Paragraph 0032; 0033; 0034; 0035; 0036; 0037; 0038-0041 |
2,3-DIFLUORO-6-NITROPHENOL Preparation Products And Raw materials
| Raw materials | 1,2,3-Trifluoro-4-nitrobenzene-->Dimethyl sulfoxide-->Potassium hydroxide |
| Preparation Products | Levofloxacin |
