2,4-DINITRO-5-FLUOROANILINE CAS 367-81-7
Introduction：Basic information about 2,4-DINITRO-5-FLUOROANILINE CAS 367-81-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2,4-DINITRO-5-FLUOROANILINE Basic information
| Product Name: | 2,4-DINITRO-5-FLUOROANILINE |
| Synonyms: | LABOTEST-BB LT00159531;2,4-DINITRO-5-FLUOROANILINE;5-FLUORO-2,4-DINITROANILINE;2-4-DINITRO-5-FLUOROANILINE CRYSTALLINE;2 4-DINITRO-5-FLUOROANILINE 97%;2,4-Dinitro-5-fluoroaniline97%;2,4-DINITRO-5-FLUOROANILINE 98+%;Bergmanns Reagent, DNFA |
| CAS: | 367-81-7 |
| MF: | C6H4FN3O4 |
| MW: | 201.11 |
| EINECS: | 206-700-4 |
| Product Categories: | |
| Mol File: | 367-81-7.mol |
2,4-DINITRO-5-FLUOROANILINE Chemical Properties
| Melting point | 185-190 °C(lit.) |
| Boiling point | 425.0±40.0 °C(Predicted) |
| density | 1.681 |
| refractive index | 1.3773 |
| storage temp. | 2-8°C |
| pka | -4.54±0.10(Predicted) |
| form | powder to crystal |
| color | Light yellow to Yellow |
| CAS DataBase Reference | 367-81-7(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi,T |
| Risk Statements | 36/37/38-23-22 |
| Safety Statements | 26-36-24/25 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| F | 1-8-10 |
| Hazard Note | Toxic |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29214200 |
| Synthesis | 327-92-4 367-81-7 General procedure for the synthesis of 5-fluoro-2,4-dinitroaniline from 1,5-difluoro-2,4-dinitrobenzene: 2.0 equivalents (1.02 mL) of ammonia were slowly added dropwise to a solution of 1.0 equivalents (4.0 mmol) of 1,5-difluoro-2,4-dinitrobenzene (DFDNB, 1) dissolved in 40 mL of THF under magnetic stirring. The reaction mixture was continued to be stirred at room temperature for 30 min. After removing the solvent by evaporation under reduced pressure, water was added to precipitate the product. The crude product 5-fluoro-2,4-dinitroaniline (2) was collected by filtration and washed well with water. The target product 5-fluoro-2,4-dinitroaniline was finally obtained in 99% yield and >99% purity by HPLC. |
| References | [1] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 14, p. 4189 - 4192 [2] Recueil des Travaux Chimiques des Pays-Bas, 1916, vol. 35, p. 142 [3] Chem. Zentralbl., 1913, vol. 84, # II, p. 760 |
2,4-DINITRO-5-FLUOROANILINE Preparation Products And Raw materials
| Raw materials | 2,4-DINITRO-5-FLUOROACETANILIDE-->1,5-Difluoro-2,4-dinitrobenzene-->Tetrahydrofuran-->Ammonia |
