2',6'-DIHYDROXY-4'-METHOXYCHALCONE CAS 18956-15-5

Introduction：Basic information about 2',6'-DIHYDROXY-4'-METHOXYCHALCONE CAS 18956-15-5, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2',6'-DIHYDROXY-4'-METHOXYCHALCONE Basic information

• Product Name: 2',6'-DIHYDROXY-4'-METHOXYCHALCONE
• Synonyms: DIHYDROXY-4'-METHOXYCHALCONE, 2',6'-;(E)-1-(2,6-DIHYDROXY-4-METHOXY-PHENYL)-3-PHENYL-PROPENONE;2',6'-DIHYDROXY-4'-METHOXYCHALCONE;2-Propen-1-one,1-(2,6-dihy;(E)-1-(2,6-Dihydroxy-4-methoxy-phenyl)-3-phenyl-;(E)-2',6'-Dihydroxy-4'-methoxychalcone;Pinostrobin chalcone;Pistrobin chalcone
• CAS: 18956-15-5
• MF: C16H14O4
• MW: 270.28
• EINECS: 200-258-5
• Product Categories: Chalcones
• Mol File: 18956-15-5.mol

2',6'-DIHYDROXY-4'-METHOXYCHALCONE Chemical Properties

• Melting point: 145°C
• Boiling point: 521.1±50.0 °C(Predicted)
• density: 1.282±0.06 g/cm3(Predicted)
• storage temp.: 2-8°C
• solubility: DMSO: Soluble: =10 mg/ml Ethanol: Soluble: =10 mg/ml
• form: Solid
• pka: 6.70±0.40(Predicted)
• color: Light yellow to orange
• InChI: 1S/C16H14O4/c1-20-12-9-14(18)16(15(19)10-12)13(17)8-7-11-5-3-2-4-6-11/h2-10,18-19H,1H3/b8-7+
• InChIKey: CUGDOWNTXKLQMD-BQYQJAHWSA-N
• SMILES: O(C)c1cc(c(c(c1)O)C(=O)\C=C\c2ccccc2)O

Safety Information

• WGK Germany: WGK 3
• Storage Class: 11 - Combustible Solids

2',6'-DIHYDROXY-4'-METHOXYCHALCONE Usage And Synthesis

Uses

Pinostrobin Chalcone is an estrogenic compound from the plant leaves of Carya cathayensis Sarg.

Definition

ChEBI: Pinostrobin chalcone is a member of chalcones.

References

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[2] E C TORRES-SANTOS. Selective effect of 2’,6’-dihydroxy-4’-methoxychalcone isolated from Piper aduncum on Leishmania amazonensis.[J]. Antimicrobial Agents and Chemotherapy, 1999, 43 5: 1234-1241. DOI: 10.1128/aac.43.5.1234
[3] SRI NURESTRI ABDUL MALEK. Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.[J]. Molecules, 2011, 16 1: 583-589. DOI: 10.3390/molecules16010583
[4] NEERAJ K. PATEL  Kamlesh K B. Pinostrobin and Cajanus lactone isolated from Cajanus cajan (L.) leaves inhibits TNF-α and IL-1β production: In vitro and in vivo experimentation[J]. Phytomedicine, 2014, 21 7: Pages 946-953. DOI: 10.1016/j.phymed.2014.02.011