Introduction：Basic information about 2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL CAS 86259-87-2, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL Basic information
| Product Name: | 2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL |
| Synonyms: | 2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL;TETRAETHYLENE GLYCOL MONOBENZYL ETHER;Benzyl-PEG4-alcohol;13-Phenyl-3,6,9,12-tetraoxatridecan-1-ol;BnO-PEG4-OH;1-Phenyl-2,5,8,11-tetraoxatridecan-13-ol;Benzyl-PEG5-alcohol;CAS_86259-87-2 |
| CAS: | 86259-87-2 |
| MF: | C15H24O5 |
| MW: | 284.35 |
| EINECS: | |
| Product Categories: | Monofunctional Ethylene Glycols;Ethylene Glycols & Monofunctional Ethylene Glycols;peg |
| Mol File: | 86259-87-2.mol |
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2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL Chemical Properties
| Boiling point | 170-174 °C(Press: 25 Torr) |
| density | 1.10 |
| refractive index | 1.4980 to 1.5020 |
| storage temp. | 2-8°C |
| solubility | Chloroform (Sparingly), DMSO (Sparingly) |
| form | Oil |
| pka | 14.36±0.10(Predicted) |
| color | Pale Yellow to Light Yellow |
| InChI | InChI=1S/C15H24O5/c16-6-7-17-8-9-18-10-11-19-12-13-20-14-15-4-2-1-3-5-15/h1-5,16H,6-14H2 |
| InChIKey | QDPIVUQXPXUNLN-UHFFFAOYSA-N |
| SMILES | C(O)COCCOCCOCCOCC1=CC=CC=C1 |
| CAS DataBase Reference | 86259-87-2 |
Safety Information
2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL Usage And Synthesis
| Description | Benzyl-PEG5-alcohol is a PEG linker with a acid labile, benzyl group and a reactive primary alcohol. The hydroxyl group can react to further derivatize the compound. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. |
| Uses | BnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| IC 50 | PEGs |
| References | [1] Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1. |
2-[2-[2-[2-(BENZYLOXY)ETHOXY]ETHOXY]ETHOXY]ETHANOL Preparation Products And Raw materials
| Preparation Products | 3,6,9,12,15,18,21,24,27,30,33,36-dodecaoxaoctatriacontane-1,38-diol-->Dodecaethylene glycol monomethyl ether-->Benzyl-PEG8-THP-->1,27-Diphenyl-2,5,8,11,14,17,20,23,26-nonaoxaheptacosane |
