Introduction：Basic information about 2-Aminothiazole-4-acetic acid CAS 29676-71-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
2-Aminothiazole-4-acetic acid Basic information
| Product Name: | 2-Aminothiazole-4-acetic acid |
| Synonyms: | (2-AMino-1,3-thiazol-4-yl)acetic acid;2-AMino-4-thiazolacetic acid;Ceftibuten Related Impurity 2;2-(2-amino-1,3-thiazol-4-yl)ethanoic acid;Ethyl-2-(2-aminothiazol-4-yl)-2-oxo-acetate(EAOA);2-Aminothiazol-4-acetic aCld;ATAH2-(2-Aminothiazol-4-yl) acetic acid;2-(2-azaniumyl-1,3-thiazol-4-yl)acetate |
| CAS: | 29676-71-9 |
| MF: | C5H6N2O2S |
| MW: | 158.18 |
| EINECS: | 249-769-6 |
| Product Categories: | Building Blocks;Heterocyclic Building Blocks;Organic acids;(intermediate of cefotiam);Cephalosporins;Thiazoles;Nitrogen cyclic compounds;Sulphur Derivatives;Heterocyclic Compounds;29676-71-9 |
| Mol File: | 29676-71-9.mol |
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2-Aminothiazole-4-acetic acid Chemical Properties
| Melting point | 130 °C (dec.)(lit.) |
| Boiling point | 399.0±17.0 °C(Predicted) |
| density | 1.367 (estimate) |
| vapor pressure | 1.03-1.15hPa at 20℃ |
| refractive index | 1.6430 (estimate) |
| storage temp. | -20°C |
| solubility | DMSO (Slightly) |
| pka | 3.20±0.10(Predicted) |
| form | solid |
| color | White |
| Water Solubility | 6.5 g/L (20 ºC) |
| BRN | 127415 |
| Stability: | Unstable in Solution |
| InChI | 1S/C5H6N2O2S/c6-5-7-3(2-10-5)1-4(8)9/h2H,1H2,(H2,6,7)(H,8,9) |
| InChIKey | DYCLHZPOADTVKK-UHFFFAOYSA-N |
| SMILES | Nc1nc(CC(O)=O)cs1 |
| LogP | -2.13 at 20℃ and pH4.54-4.64 |
| CAS DataBase Reference | 29676-71-9(CAS DataBase Reference) |
| EPA Substance Registry System | 2-Amino-4-thiazoleacetic acid (29676-71-9) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| HS Code | 29349990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
2-Aminothiazole-4-acetic acid Usage And Synthesis
| Chemical Properties | Almost white to light beige crystalline powder |
| Uses | 2-Amino-4-thiazoleacetic acid has been used in:
- preparation of poly(2-amino-4-thiazoleacetic acid)/multiwalled carbon nanotubes modified glassy carbon electrodes, for the voltammetric determination of copper ions
- electrochemical synthesis of novel thiozole-based copolymer with 2-aminothiazole
- preparation of aquabis(2-amino-1,3-thiazole-4-acetato-κ2O,N3)nickel (II)
|
| General Description | Light orange powder. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | An organosulfide and amine derivative, carboxylic acid. Look at Reactive Groups 20 (organosulfides), 7 (amines), and 3 (carboxylic acids) may give indications about reactive tendencies. |
| Fire Hazard | Flash point data for 2-Aminothiazol-4-acetic acid are not available. 2-Aminothiazol-4-acetic acid is probably combustible. |
2-Aminothiazole-4-acetic acid Preparation Products And Raw materials
| Raw materials | Thiourea-->Ethyl 2-amino-4-thiazoleacetate |
| Preparation Products | Cefodizime-->2-Amino-((1-carboxy-1-methyl ethoxy)imino)-4-thiazoleacetic acid-->METHYL 2-AMINO-4-THIAZOLEACETATE-->Mirabegron |
