2-Propylpiperidine CAS 3238-60-6

Introduction：Basic information about 2-Propylpiperidine CAS 3238-60-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

2-Propylpiperidine Basic information

• Product Name: 2-Propylpiperidine
• Synonyms: 2-PRIOPYLPIPERIDINE;2-PROPYLPIPERIDINE;2-N-PROPYLPIPERIDINE;(2R)-2-Propylpiperidine;(R)-2-Propylpiperidine;DL-CONIINE;CONIINE;CONIINE, DL-
• CAS: 3238-60-6
• MF: C8H17N
• MW: 127.23
• EINECS: 221-801-3
• Product Categories: Alkaloids
• Mol File: 3238-60-6.mol

2-Propylpiperidine Chemical Properties

• Melting point: -2℃
• Boiling point: 56-60 °C(Press: 13 Torr)
• density: 0.85 g/mL at 25 °C(lit.)
• storage temp.: Sealed in dry,2-8°C
• pka: pK1:11.24(+1) (25°C,μ=0.5)
• form: liquid
• color: , clear colorless to yellow-green
• CAS DataBase Reference: 3238-60-6(CAS DataBase Reference)

Safety Information

• Hazard Codes: T
• Risk Statements: 23/24/25-40
• Safety Statements: 22-36/37/39-45
• RIDADR: UN 2810 6.1/PG 2
• WGK Germany: 3
• HazardClass: IRRITANT
• HS Code: 2933399990
• Toxicity: Piperidine alkaloid obtainedfrom poison hemlock, Conium maculatum. Alkaline, steamvolatile liquid (b.p. 167_x0003_C), mousy odor. Darkens and polymerizesin air. It can be reduced at high temperature with HIto n-octane and oxidized to pyridine-1-carboxylic acid. Thehydrochloride is used as an antispasmodic.

2-Propylpiperidine Usage And Synthesis

Chemical Properties

Colorless liquid; darkens on exposure tolight and air; polymerizes; boils at 166°C(330.8°F); melts at -2°C (28.4°F); alkaline, pKa 3.1; density 0.845 at 20°C (68°F);slightly soluble in water and chloroform,readily soluble in most organic solvents.

Uses

Coniine is present in all parts of the plantpoison hemlock (Conium maculatum). It isthe first alkaloid to be synthesized and structure determined. Because of its high toxicity,its clinical application is very limited.

Synthesis Reference(s)

Tetrahedron Letters, 26, p. 4633, 1985 DOI: 10.1016/S0040-4039(00)98771-9

Health Hazard

Coniine is a highly toxic alkaloid. Thetoxic symptoms from ingestion are weakness,drowsiness, nausea, vomiting, muscle contraction, and labored breathing. A high dosecan cause convulsions, cyanosis, asphyxia,and death. Chronic ingestion of coniine produced adverse reproductive effects and spe cific developmental abnormalities in cattles.LD50 value, oral (mice): 100 mg/kg.