3,3',4,4'-Biphenyltetramine tetrahydrochloride CAS 7411-49-6

Introduction:Basic information about 3,3',4,4'-Biphenyltetramine tetrahydrochloride CAS 7411-49-6, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

3,3',4,4'-Biphenyltetramine tetrahydrochloride Basic information

Product Name:3,3',4,4'-Biphenyltetramine tetrahydrochloride
Synonyms:DAB (DiaMinobenzidine) tetrahydrochloride;3,3-DiaMonobenzidine tetrahydrchloride;[1,1'-Biphenyl]-3,3',4,4'-tetraMine, hydrochloride (1:4);3,3′-Diaminobenzidine Peroxidase Substrate;SIGMAFAST? DAB with Metal Enhancer;DAB, 50X;DAB LIQUID SUBSTRATE DROPPER SYSTEM,*TRU -MEASURE CH;3,3',4,4'-BIPHENYLTETRAMINE 4HCL
CAS:7411-49-6
MF:C12H18Cl4N4
MW:360.11
EINECS:231-018-9
Product Categories:Industrial/Fine Chemicals;Blotting/Histochemistry SubstratesWestern Blotting;Blotting/Histochemistry SubstratesImmunohistochemistry;Liquid Substrate SystemsImmunohistochemistry;Alkaline Phosphatase;Alphabetical ListingSubstrates, Buffers&Blockers;Enzyme substrates;Detection Substrates;Enzyme Substrates;Liquid Substrate Systems;Peroxidase;Substrates for Peroxidase;Liquid Substrate SystemsEnzyme Substrates;Peroxidase Substrates;Substrates by Enzyme;amino
Mol File:7411-49-6.mol

3,3',4,4'-Biphenyltetramine tetrahydrochloride Chemical Properties

Melting point 300°C
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form tablets
color Crystals
PHpH(25℃) : 7.4~7.8
Water Solubility Soluble
Sensitive Moisture Sensitive/Air Sensitive
BRN 1212988
Stability:Hygroscopic
InChIInChI=1S/C12H14N4.4ClH/c13-9-3-1-7(5-11(9)15)8-2-4-10(14)12(16)6-8;;;;/h1-6H,13-16H2;4*1H
InChIKeyKJDSORYAHBAGPP-UHFFFAOYSA-N
SMILESC1(C2=CC=C(N)C(N)=C2)=CC=C(N)C(N)=C1.[H]Cl.[H]Cl.[H]Cl.[H]Cl
CAS DataBase Reference7411-49-6(CAS DataBase Reference)
EPA Substance Registry System[1,1'-Biphenyl]-3,3',4,4'-tetramine, tetrahydrochloride (7411-49-6)

Safety Information

Hazard Codes F,T,Xn,N
Risk Statements 23/24/25-36/38-39/23/24/25-40-20/21/22-68-45-51/53-42/43-60-61
Safety Statements 7-16-24-33-36/37-45-24/25-22-36/37/39-53-61
RIDADR UN 3316 9/PG 2
WGK Germany 3
RTECS DV8753000
3-8-10
TSCA TSCA listed
HS Code 29215900
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 4 Oral
Carc. 1B
Eye Irrit. 2
Muta. 2
Hazardous Substances Data7411-49-6(Hazardous Substances Data)
ToxicityLD50 ipr-mus: 330 mg/kg NCIBR* NIH-NCI-E-68-1311,10,73

3,3',4,4'-Biphenyltetramine tetrahydrochloride Usage And Synthesis

Chemical PropertiesGrey Solid
UsesA substrate for peroxidase, and a reagent for the spectrophotometric determination of selenium
Uses3,3′-Diaminobenzidine (DAB) Enhanced Liquid Substrate System tetrahydrochloride has been used:
  • in the detection of hydrogen peroxide in rice leaves
  • as a substrate for rabbit peroxidase in immunohistochemistry of mice brain sections
  • in immunocytochemistry of muscle-derived stem cells (MDSCs)

Uses3,3′-Diaminobenzidine tetrahydrochloride has been used for immunohistochemistry.
General Description3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase.
Biochem/physiol Actions3,3′-Diaminobenzidine (DAB) is a chromogenic substrate for peroxidase enzyme. It is converted to an insoluble precipitate after oxidation by peroxidase. This feature is exploited for visualization in histochemical (HC) and immunohistochemical (IHC) staining.
Safety ProfileSuspected carcinogen withexperimental neoplastigenic and tumorigenic data. Poisonby intraperitoneal route. When heated to decomposition itemits very toxic fumes of HCl and NOx.
Purification MethodsDissolve the salt in water and precipitate it by adding conc HCl, then drying it over solid NaOH. [Beilstein 13 IV 530.]

3,3',4,4'-Biphenyltetramine tetrahydrochloride Preparation Products And Raw materials

3,3,3-Trifluoropropylmethyldimethoxysilane CAS 358-67-8
3,3',4,4'-TETRACHLOROBIPHENYL CAS 32598-13-3
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