3-Amino-5-phenylpyrazole CAS 1572-10-7

Introduction：Basic information about 3-Amino-5-phenylpyrazole CAS 1572-10-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

3-Amino-5-phenylpyrazole Basic information

• Product Name: 3-Amino-5-phenylpyrazole
• Synonyms: SALOR-INT L317837-1EA;5-amino-3-phenyl-pyrazol;JR-8809, 5-Phenyl-1H-pyrazole-3-ylamine, 97%;5-PHENYL-2H-PYRAZOL-3-YLAMINE;5-PHENYL-1H-PYRAZOL-3-AMINE;5-PHENYL-1H-PYRAZOL-3-YLAMINE;AKOS B003768;AKOS 92617
• CAS: 1572-10-7
• MF: C9H9N3
• MW: 159.19
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrazoles;pyrazole series;Heterocyclic Compounds;Imidazoles, Pyrroles, Pyrazoles, Pyrrolidines
• Mol File: 1572-10-7.mol

3-Amino-5-phenylpyrazole Chemical Properties

• Melting point: 124-127 °C (lit.)
• Boiling point: 442.3±33.0 °C(Predicted)
• density: 1.238±0.06 g/cm3(Predicted)
• storage temp.: Keep in dark place,Inert atmosphere,Room temperature
• solubility: DMSO, Methanol
• form: Powder or Crystals
• pka: 14.80±0.10(Predicted)
• color: Red to brown
• BRN: 4947
• InChI: 1S/C9H9N3/c10-9-6-8(11-12-9)7-4-2-1-3-5-7/h1-6H,(H3,10,11,12)
• InChIKey: PWSZRRFDVPMZGM-UHFFFAOYSA-N
• SMILES: Nc1cc([nH]n1)-c2ccccc2
• CAS DataBase Reference: 1572-10-7(CAS DataBase Reference)

Safety Information

• Hazard Codes: Xi
• Risk Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• RTECS: UQ6109000
• Hazard Note: Irritant
• HS Code: 29331990
• Storage Class: 11 - Combustible Solids
• Hazard Classifications: Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
• Toxicity: mouse,LDLo,intraperitoneal,630mg/kg (630mg/kg),Farmakologiya i Toksikologiya Vol. 27, Pg. 295, 1964.

3-Amino-5-phenylpyrazole Usage And Synthesis

Chemical Properties

Off-white to cream colored crystalline powder

Uses

3-Amino-5-phenylpyrazole ((3-phenyl-1H-pyrazol-5-amine) may be used in the synthesis of the following:

• Urea derivatives by reaction with azido(6-(benzofuran-2-yl)-2-methylpyridin-3-yl) methanone.
• 2-Mercaptoacetamide analogs by treating with thioglycolic acid.
• 3-(Substituentpyrimidayl)-5,6-benzocoumarins by treating with 3-(2′-formyl-1′-chlorovinyl)-5,6-benzocoumarin.
• Substituted 2,7-diphenylpyrazolo[1,5-a]pyrimidine-5-carboxylic esters by reacting with substituted β-diketo esters.
• N-ethoxycarbonylthiourea derivative by reacting with ethoxycarbonyl isothiocyanate.
• Heterobiaryl pyrazolo[3,4-b]pyridines by reacting with indole-3-carboxaldehyde.

General Description

3-Amino-5-phenylpyrazole (3-phenyl-1H-pyrazol-5-amine), an amino pyrazole derivative, is an aza-heterocyclic amine. It has been reported to be synthesized by heating either 3-amino-4-bromo- or 3-amino-5-phenylisothiazole in the presence of anhydrous hydrazine. On reaction with ZnCl₂ it affords chlorido-tris(3-amino-5-phenyl-1Hpyrazole-N²)zinc (II) chloride.

3-Amino-5-phenylpyrazole Preparation Products And Raw materials

• Raw materials: Hydrochloric acid-->Tetrahydrofuran-->n-Butyllithium-->Sodium acetate trihydrate-->Acetophenone-->Diisopropylamine-->Semicarbazide hydrochloride