3-Amino-9-ethylcarbazole CAS 132-32-1

Introduction：Basic information about 3-Amino-9-ethylcarbazole CAS 132-32-1, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

3-Amino-9-ethylcarbazole Basic information

• Product Name: 3-Amino-9-ethylcarbazole
• Synonyms: TIMTEC-BB SBB000498;2-AMINO-9-ETHYL CARBAZOLE;3-Amino-9-ethylcarbazole,9-Ethylcarbazol-3-amine, AEC;3-Amino-9-ethylcarba;3-amino-9-ethyl-carbazol;3-amino-n-ethylcarbazol;9-Ethyl-3-carbazolamine;3-Amino-9-ethyl-9H-carbazole
• CAS: 132-32-1
• MF: C14H14N2
• MW: 210.27
• EINECS: 205-057-7
• Product Categories: Intermediates of Dyes and Pigments;Biochemistry;Enzyme;Substrates;carbazole;Carbazoles (for Conduting Polymer Research);Carbazoles;Functional Materials;Reagents for Conducting Polymer Research;buffer
• Mol File: 132-32-1.mol

3-Amino-9-ethylcarbazole Chemical Properties

• Melting point: 85-88 °C(lit.)
• Boiling point: 355C
• density: 1,15g/cm
• refractive index: 1.6180 (estimate)
• storage temp.: 2-8°C
• solubility: Chloroform (Sparingly), Methanol (Slightly)
• pka: 4.99±0.30(Predicted)
• form: tablet
• color: Brown to Very Dark Brown
• BRN: 174969
• InChI: InChI=1S/C14H14N2/c1-2-16-13-6-4-3-5-11(13)12-9-10(15)7-8-14(12)16/h3-9H,2,15H2,1H3
• InChIKey: OXEUETBFKVCRNP-UHFFFAOYSA-N
• SMILES: N1(CC)C2=C(C=CC=C2)C2=C1C=CC(N)=C2
• CAS DataBase Reference: 132-32-1(CAS DataBase Reference)
• NIST Chemistry Reference: 9H-carbazol-3-amine, 9-ethyl-(132-32-1)
• EPA Substance Registry System: 3-Amino-9-ethylcarbazole (132-32-1)

Safety Information

• Hazard Codes: T
• Risk Statements: 25-36/37/38-40-23/24/25-45
• Safety Statements: 45-36/37/39-26-22-53
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• RTECS: FE3590000
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29339900
• Storage Class: 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
• Hazard Classifications: Acute Tox. 3 Oral Carc. 1B
• Hazardous Substances Data: 132-32-1(Hazardous Substances Data)

3-Amino-9-ethylcarbazole Usage And Synthesis

Chemical Properties

3-Amino-9-ethylcarbazole is a brownish or tannish powder and chunks. It is utilized for producing dyes and pigments, as well as serving as an indicator for peroxidase in cells and a biological stain.

Uses

3-Amino-9-ethylcarbazole (AEC) has been used as a chromogen in immunohistochemistry to visualize the cells. It has also been used as a substrate in enzyme-linked immune absorbent spot (ELISpot).

Preparation

Prepared by reducing 3-nitro-N-ethylcarbazole with sodium sulfide.

Definition

ChEBI: 3-Amino-9-ethylcarbazole is a hydrochloride salt and free amine solid compound. It has been used to visualize the bound primary antibody by using a streptavidin method. It has also been used in visualizing tissue sections from tumour samples.

General Description

Tan powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Hazard

Questionable carcinogen; poison.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 3-Amino-9-ethylcarbazole emits toxic fumes.

Fire Hazard

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

Safety Profile

Suspected carcinogen with experimental carcinogenic data. Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx,.

Potential Exposure

Plant workers engaged in the manufacture of this compound and its use in pigment manufacture. Laboratory workers using this material in colorimetric enzyme assays and as a biological stain

Shipping

UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

3-Amino-9-ethylcarbazole neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.

Waste Disposal

Incinerator equipped with a scrubber or thermal unit to reduce nitrogen oxides emissions.

3-Amino-9-ethylcarbazole Preparation Products And Raw materials

• Raw materials: Ethanol-->Hydrochloric acid-->Methanol-->Acetic acid-->N,N-Dimethylformamide-->Nitric acid-->Ammonium hydroxide-->Iron-->Diethyl oxalate-->Sodium sulfide-->Potassium tert-butoxide-->Carbazole-->9-Ethyl-3-nitrocarbazole-->Imidazole-2-carboxaldehyde
• Preparation Products: Permanent Violet RL-->REMASTRAL BLUE FFRL-->N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-Morpholin-4-yl-propyl)-pyriMidine-2,4-diaMine-->DIRECT BLUE 108-->9H-Carbazole, 9-ethyl-3-iodo-