Introduction：Basic information about 4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID CAS 380430-57-9, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID Basic information
| Product Name: | 4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID |
| Synonyms: | AKOS BRN-0584;(4-METHYLSULFONYL)AMINOBENZENEBORONIC ACID;4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID;4-METHANESULFONYLAMINOPHENYLBORONIC ACID;4-N-(METHANESULFONAMIDE)PHENYLBORONIC ACID;N-4-METHANESULFONAMIDEPHENYLBORONIC ACID;Boronic acid, [4-[(methylsulfonyl)amino]phenyl]- (9CI);4-(Methylsulphonyl)aminobenzeneboronic acid 95% |
| CAS: | 380430-57-9 |
| MF: | C7H10BNO4S |
| MW: | 215.03 |
| EINECS: | |
| Product Categories: | Aryl Boronic Acids;Boronic Acids and Derivatives;BORONICACID;Chemical Synthesis;Monosubstituted Aryl Boronic Acids;Organometallic Reagents;Amines;blocks;BoronicAcids;Sulfonamides;Boronic acids |
| Mol File: | 380430-57-9.mol |
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4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID Chemical Properties
| Melting point | 148-154°C |
| Boiling point | 421.8±55.0 °C(Predicted) |
| density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,2-8°C |
| form | solid |
| pka | 8.42±0.10(Predicted) |
| color | Beige |
| InChI | 1S/C7H10BNO4S/c1-14(12,13)9-7-4-2-6(3-5-7)8(10)11/h2-5,9-11H,1H3 |
| InChIKey | NDVJJEADFLTFCD-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)Nc1ccc(cc1)B(O)O |
| CAS DataBase Reference | 380430-57-9(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36/37/39 |
| WGK Germany | 1 |
| HS Code | 2931900090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID Usage And Synthesis
| Uses | Reactant for preparation of:• ;Potent and selective inhibitors of IKK-β1• ;Inhibitors for treatment of osteoporosis2• ;Inhibitors of human farnesyl pyrophosphate synthase3• ;Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors4 |
| Uses | Reactant for preparation of:
- Potent and selective inhibitors of IKK-β
- Inhibitors for treatment of osteoporosis
- Inhibitors of human farnesyl pyrophosphate synthase
- Suzuki-type Pd(0) coupling reactions in the synthesis of 2-arylpurines as Cdk inhibitors
|
4-(METHYLSULFONYLAMINO)PHENYLBORONIC ACID Preparation Products And Raw materials
| Raw materials | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)aniline-->Methanesulfonyl chloride |
| Preparation Products | Methanesulfonamide, N-[4-(6-chloro-3-pyridazinyl)phenyl]- |
