4,4'-Oxydianiline CAS 101-80-4
Introduction：Basic information about 4,4'-Oxydianiline CAS 101-80-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4,4'-Oxydianiline Basic information
| Product Name: | 4,4'-Oxydianiline |
| Synonyms: | 4,4'-Oxydianiline purified by sublimation, 99%;4,4'-Diaminodiphenyl ether for synthesis;BIO-FARMA BF003088;BIS(4-AMINOPHENYL) ETHER;BIS(P-AMINOPHENYL)ETHER;4-AMINOPHENYL ETHER;4,4-OXYDIANILINE;4,4'-ODA |
| CAS: | 101-80-4 |
| MF: | C12H12N2O |
| MW: | 200.24 |
| EINECS: | 202-977-0 |
| Product Categories: | Monomer for Polyimide film;Diphenyl Ethers (for High-Performance Polymer Research);Biphenyl & Diphenyl ether;Functional Materials;Reagent for High-Performance Polymer Research;Building Blocks;Intermediates of Dyes and Pigments;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks;Polyamines;Pyridines;101-80-4 |
| Mol File: | 101-80-4.mol |
4,4'-Oxydianiline Chemical Properties
| Melting point | 188-192 °C(lit.) |
| Boiling point | 190 °C (0.1 mmHg) |
| density | 1.1131 (rough estimate) |
| vapor pressure | 10 mm Hg ( 240 °C) |
| refractive index | 1.6660 (estimate) |
| Fp | 426 °F |
| storage temp. | Store below +30°C. |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 5.49±0.10(Predicted) |
| color | White |
| Water Solubility | Insoluble. <0.01 g/100 mL at 15 ºC |
| BRN | 475735 |
| Stability: | Stable. Combustible. Incompatible with strong oxidizing agents. Hygroscopic. |
| Major Application | cleaning products cosmetics environmental food and beverages personal care |
| InChI | 1S/C12H12N2O/c13-9-1-5-11(6-2-9)15-12-7-3-10(14)4-8-12/h1-8H,13-14H2 |
| InChIKey | HLBLWEWZXPIGSM-UHFFFAOYSA-N |
| SMILES | Nc1ccc(Oc2ccc(N)cc2)cc1 |
| LogP | 0.72 at 20℃ |
| CAS DataBase Reference | 101-80-4(CAS DataBase Reference) |
| IARC | 2B (Vol. 29, Sup 7) 1987 |
| NIST Chemistry Reference | Benzenamine, 4,4'-oxybis-(101-80-4) |
| EPA Substance Registry System | 4,4'-Diaminodiphenyl ether (101-80-4) |
Safety Information
| Hazard Codes | T,N |
| Risk Statements | 45-46-23/24/25-51/53-62-36/37/38-22-50/53-43 |
| Safety Statements | 53-45-61-36/37-26-20-60 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | BY7900000 |
| TSCA | TSCA listed |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29222900 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Aquatic Chronic 1 Carc. 1B Muta. 1B Repr. 2 Skin Sens. 1 STOT RE 2 Oral |
| Hazardous Substances Data | 101-80-4(Hazardous Substances Data) |
| Toxicity | LD50 orl-rat: 725 mg/kg HYSAAV 33,137,68 |
| Uses | Bis(p-aminophenyl) Ether is a reagent used in the preparation of polyimide-silica composite membranes for gas separation techniques. In addition, it is used in the synthesis of polymer films for electrolyte membranes. Dyes and metabolites, Environmental Testing |
| Description | 4,40-Oxydianiline is a white crystalline solid,or a beige powder. Molecular weight =200.26; Boilingpoint ≥300℃ (sublimes); Freezing/Meltingpoint = 186-187℃; Flash point =219℃. Very slightlysoluble in water. |
| Chemical Properties | Colorless crystalline |
| Chemical Properties | 4-Aminophenyl ether is a resin used in the manufacture of a variety of industrial products. For example as, insulating varnishes, flame-retardant fi bers, wire enamels, coatings, and fi lms. It is also used for the manufacture of other fi re-resistant products. |
| Chemical Properties | 4,40′-Oxydianiline is a white crystalline solid,or a beige powder. |
| Uses | 4,4＇-Oxydianiline has been used to produce polyimide resins. |
| Uses | Bis(p-aminophenyl) Ether is a reagent used in the preparation of polyimide-silica composite membranes for gas separation techniques. In addition, it is used in the synthesis of polymer films for electrolyte membranes. |
| Uses | 4,4'-diaminodiphenylether be used for preparation polyimide and epoxy resin material. |
| Production Methods | 4-Aminophenyl ether was produced in relatively large volume(on the order of 100,000–1,000,000 lb) in the 1970s buthas since declined significantly. The compound is usedprimarily in the production of polyimide and polyesterimideresins. These resins are used in the manufacture of temperature-resistant products such as wire enamels, coatings, film,insulating varnishes, and flame-retardant fibers. |
| Definition | ChEBI: 4-Aminophenyl ether is an aromatic ether. |
| General Description | Odorless colorless crystals or an odorless fine, beige powder. |
| Air & Water Reactions | Insoluble in water. |
| Reactivity Profile | 4,4'-Oxydianiline oxidizes readily in air to form unstable peroxides that may explode spontaneously [Bretherick, 1979 p.151-154, 164]. A mixture of liquid air and diethyl ether exploded spontaneously [MCA Case History 616(1960)]. |
| Health Hazard | 4-Aminophenyl ether is highly toxic to animals. There is suffi cient evidence as a carcinogenicity and has caused adenomas and carcinomas in the thyroid and liver of experimental rats. |
| Fire Hazard | 4,4'-Oxydianiline is combustible. |
| Flammability and Explosibility | Not classified |
| Safety Profile | Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx |
| Potential Exposure | Intermediate in the manufacture ofhigh-temperature-resistant, straight polyimide and poly(esterimide) resins capable of withstanding temperatures ofUp to 480°C for short periods or 260°C for prolonged periodsof time. Some p-phenylenediamine compounds havebeen used as rubber components, and DFG warns of dangerof skin sensitization. |
| First aid | Skin Contact: Flood all areas of body that havecontacted the substance with water. Do not wait to removecontaminated clothing; do it under the water stream. Usesoap to help assure removal. Isolate contaminated clothingwhen removed to prevent contact by others. EyeContact: Remove any contact lenses at once. Immediatelyflush eyes well with copious quantities of water or normalsaline for at least 20-30 min. Seek medical attention.Inhalation: Leave contaminated area immediately; breathefresh air. Proper respiratory protection must be supplied toany rescuers. If coughing, difficult breathing, or any othersymptoms develop, seek medical attention at once, even ifsymptoms develop many hours after exposure. Ingestion:Contact a physician, hospital, or poison center at once. Ifthe victim is unconscious or convulsing, do not inducevomiting or give anything by mouth. Assure that thepatient’s airway is open and lay him on his side with hishead lower than his body and transport immediately to amedical facility. If conscious and not convulsing, give aglass of water to dilute the substance. Vomiting should notbe induced without a physician’s advice. |
| Carcinogenicity | 4,4′-Oxydianiline is reasonably anticipated to be a human carcinogenbased on sufficient evidence of carcinogenicity from studies in experimental animals. |
| storage | Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with thischemical you should be trained on its proper handling andstorage. Store in a refrigerator under an inert atmosphere.Protect from exposure to light and oxidizing agents. A regulated, marked area should be established where this chemical is handled, used, or stored in compliance with OSHAStandard 1910.1045. |
| Shipping | UN2811 Toxic solids, organic, n.o.s., HazardClass: 6.1; Labels: 6.1-Poisonous materials, Technical NameRequired. UN3077 Environmentally hazardous substances,solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardousmaterial, Technical Name Required. |
| Incompatibilities | Incompatible with oxidizers (chlorates,nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions.Keep away from alkaline materials, strong bases,strong acids, oxoacids, and epoxides. Slowly hydrolyzes inwater, releasing ammonia, and forming acetate salts.Decomposes at 265C releasing toxic oxides of nitrogen,sulfur, and carbon. Decomposed by strong ultraviolet light. |
| Waste Disposal | Incineration with provisionfor nitrogen oxides removal from flue gases. |
4,4'-Oxydianiline Preparation Products And Raw materials
| Raw materials | Hydrochloric acid-->Sodium carbonate-->Sodium nitrite-->Ammonium hydroxide-->Ammonium chloride-->Iron-->Activated carbon-->Potassium chloride-->EMULSIFIER-->Citric acid-->Nitrobenzene-->Sodium formate-->4-Nitrophenol |
| Preparation Products | Polyimide film-->N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE-->4,4'-DINITRODIPHENYL ETHER-->4,4'-Oxydiphenol-->Acid Green 54 |
