Introduction：Basic information about 4-Chloro-2-fluorobenzoic acid CAS 446-30-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chloro-2-fluorobenzoic acid Basic information
| Product Name: | 4-Chloro-2-fluorobenzoic acid |
| Synonyms: | 4-Chloro-2-Fluorobenzoic;4-Chloro-2-fluorobenzoic acid 98%;4-Chloro-2-fluorobenzoicacid98%;Benzoic acid, 4-chloro-2-fluoro-;4-Chloro-2-Fluorobenzoic Acid 2-Fluoro-4-Chlorobenzoic Acid;4-CHLORO-2-FLUOROBENZOIC ACID 98%(HPL&;RARECHEM AL BO 0755;TIMTEC-BB SBB003797 |
| CAS: | 446-30-0 |
| MF: | C7H4ClFO2 |
| MW: | 174.56 |
| EINECS: | 207-162-3 |
| Product Categories: | Fluorine series;Benzoic acid;Fluorobenzene;API intermediates;Acids & Esters;Chlorine Compounds;Fluorine Compounds;C7;Carbonyl Compounds;Carboxylic Acids;blocks;Carboxes;FluoroCompounds;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts |
| Mol File: | 446-30-0.mol |
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4-Chloro-2-fluorobenzoic acid Chemical Properties
| Melting point | 204-208 °C (lit.) |
| Boiling point | 274.7±20.0 °C(Predicted) |
| density | 1.4016 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 3.04±0.10(Predicted) |
| form | powder to crystal |
| color | White to Almost white |
| Water Solubility | insoluble |
| BRN | 973358 |
| InChI | InChI=1S/C7H4ClFO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11) |
| InChIKey | ZLPXBWMVZANJJQ-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(Cl)C=C1F |
| CAS DataBase Reference | 446-30-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Chloro-2-fluorobenzoic acid(446-30-0) |
| EPA Substance Registry System | Benzoic acid, 4-chloro-2-fluoro- (446-30-0) |
Safety Information
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-22 |
| Safety Statements | 26-36-37/39 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HazardClass | IRRITANT |
| HS Code | 29163990 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
4-Chloro-2-fluorobenzoic acid Usage And Synthesis
| Chemical Properties | White to light yellow crystal powder |
| Uses | 4-Chloro-2-fluorobenzoic acid may be used in the following studies:
- As starting reagent for the synthesis of furosemide.
- Synthesis of 4′-chloro-2′-fluoroacetophenone.
- Synthesis of novel herbicidal isoxazolecarboxamides.
- Preparation of potential liquid crystals.
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| General Description | 4-Chloro-2-fluorobenzoic acid is a halogen benzoic acid. It is a non-liquid crystalline carboxylic acid derivative. It has been reported to form hydrogen bonded complexes with benzoylhydrazine-based azobenzene compound. Octanol/water partition coefficient Kow of 4-chloro-2-fluorobenzoic acid has been determined by shake-flask method. |
4-Chloro-2-fluorobenzoic acid Preparation Products And Raw materials
| Raw materials | 4-Chloro-2-fluorotoluene-->4''-CHLORO-2''-FLUOROACETOPHENONE |
| Preparation Products | 4-Chloro-2-fluoroaniline-->2-Fluoro-4-chlorobenzoyl chloride-->4-Chloro-2-fluorobenzenethiol |
