4-Chloro-2-nitroaniline CAS 89-63-4

Introduction：Basic information about 4-Chloro-2-nitroaniline CAS 89-63-4, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

4-Chloro-2-nitroaniline Basic information

• Product Name: 4-Chloro-2-nitroaniline
• Synonyms: fastred2ncsalt;redbase3gl;redbasecibavi;redbaseirgavi;redsaltcibavi;redsaltnbgl;Sanyo Fast Red Salt 3GL;sanyofastredsalt3gl
• CAS: 89-63-4
• MF: C6H5ClN2O2
• MW: 172.57
• EINECS: 201-925-4
• Product Categories: Dyestuff Intermediates;Amines;Anilines, Aromatic Amines and Nitro Compounds;Organics;Aromatics;Mutagenesis Research Chemicals;Intermediates of Dyes and Pigments
• Mol File: 89-63-4.mol

4-Chloro-2-nitroaniline Chemical Properties

• Melting point: 117-119 °C(lit.)
• Boiling point: 200°C (rough estimate)
• density: 1.37
• refractive index: 1.6460 (estimate)
• Fp: 191 °C
• storage temp.: room temp
• solubility: 0.5g/l (anhydrous substance)
• form: Crystalline Powder or Chunks
• Colour Index: 37040
• pka: pK1: 1.10(+1) (25°C)
• color: Orange
• PH: 7 (0.5g/l, H2O, 20℃)
• Water Solubility: INSOLUBLE
• BRN: 512436
• Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
• InChI: 1S/C6H5ClN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2
• InChIKey: PBGKNXWGYQPUJK-UHFFFAOYSA-N
• SMILES: Nc1ccc(Cl)cc1[N+]([O-])=O
• CAS DataBase Reference: 89-63-4(CAS DataBase Reference)
• NIST Chemistry Reference: Aniline, 4-chloro-2-nitro-(89-63-4)
• EPA Substance Registry System: 4-Chloro-2-nitroaniline (89-63-4)

Safety Information

• Hazard Codes: T+,N,T
• Risk Statements: 26/27/28-33-51/53
• Safety Statements: 28-36/37-45-61-28A
• RIDADR: UN 2237 6.1/PG 3
• WGK Germany: 2
• RTECS: BX1575000
• Autoignition Temperature: 964 °F
• Hazard Note: Very Toxic
• TSCA: TSCA listed
• HazardClass: 6.1
• PackingGroup: III
• HS Code: 29214210
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
• Hazard Classifications: Acute Tox. 1 Dermal Acute Tox. 2 Inhalation Acute Tox. 2 Oral Aquatic Acute 1 Aquatic Chronic 2 STOT RE 2
• Hazardous Substances Data: 89-63-4(Hazardous Substances Data)

4-Chloro-2-nitroaniline Usage And Synthesis

Chemical Properties

bright orange powder

Uses

A nitro-aromatic amine with mutagenicity and carcinogenicity

Uses

4-Chloro-2-nitroaniline is usedalmost exclusively as an intermediate in the synthesis ofpigments.The greatest potential for human exposure to 4-chloro-2-nitroaniline is in production and use of pigments made fromthe compound.

Uses

4-Chloro-2-nitroaniline is used as pharmaceutical intermediate.

Production Methods

1,4-Dichloro-2-nitrobenzene is aminated at 165 ℃ by using a process similar to that described for 2- nitroaniline.

Preparation

4-Chloro-2-nitrobenzenamine of chlorine.

General Description

Bright orange powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Chloro-2-nitroaniline forms explosive products on reaction with nitric acid. Can react with oxidizing agents.

Hazard

Toxic by ingestion and inhalation.

Fire Hazard

4-Chloro-2-nitroaniline is probably combustible.

Purification Methods

Crystallise the aniline from hot H2O (m 115.8-116o), EtOH, EtOH/H2O or *C6H6, and dry it for 10hours at 60o in vacuo. It has m 115.5-116o after sublimation. [Beilstein 12 H 729, 12 I 355, 12 II 396, 12 III 1649, 12 IV 1669.]

4-Chloro-2-nitroaniline Preparation Products And Raw materials

• Raw materials: 2,5-Dichloronitrobenzene-->4-Chloro-2-nitroaniline
• Preparation Products: Quizalofop-p-ethyl-->HANSA YELLOW 10G-->2-(2'-Hydroxy-3',5'-di-tert-butylphenyl)-5-chlorobenzotriazole-->N-Acetyl-N-(4-chloro-2-nitrophenyl)acetamide-->5-[(4-chloro-2-nitrophenyl)azo]-1-ethyl-1,2-dihydro-6-hydroxy-4-methyl-2-oxonicotinonitrile-->1,2,3,4-tetrahydro-Phenazine-->N-(2-AMINO-4-CHLOROPHENYL)ANTHRANILIC ACID-->8-chloro-1-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione-->4-AMINO-3-NITROPHENYLBORONIC ACID, PINACOL ESTER-->5-CHLORO-2-IODOANILINE-->UV-320-->2,3,6-TRICHLOROQUINOXALINE-->DISPERSE YELLOW 211-->4-Chloro-2-nitroaniline