Introduction：Basic information about 4-Chloro-5-sulphamoylbenzoic acid CAS 1205-30-7, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chloro-5-sulphamoylbenzoic acid Basic information
| Product Name: | 4-Chloro-5-sulphamoylbenzoic acid |
| Synonyms: | Indapamide USP Impurity E;4-CHLORO-3-SULFAMOYLBENZOIC ACIDFRUSEMIDE;Benzoic acid, 3-(aminosulfonyl)-4-chloro-;Chloro sulfamoylbenzoic acid;4-Chloro-5-sulphamoy;4-(chlorosulfaMoyl)benzoic acid;4-Chloro-3-sulfaminebenzoic;4-CHLORO-3-SULFONYL AMIDE BENZOIC ACID |
| CAS: | 1205-30-7 |
| MF: | C7H6ClNO4S |
| MW: | 235.64 |
| EINECS: | 214-882-1 |
| Product Categories: | Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfur Compounds;Amines;Aromatics;Sulfur & Selenium Compounds;Organic Building Blocks;Sulfonamides/Sulfinamides;Sulfur Compounds;BenzoicAcidDerivative;Organic acids;API intermediates |
| Mol File: | 1205-30-7.mol |
|
4-Chloro-5-sulphamoylbenzoic acid Chemical Properties
| Melting point | 256-258 °C (lit.) |
| Boiling point | 502.4±60.0 °C(Predicted) |
| density | 1.649±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.44±0.10(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C7H6ClNO4S/c8-5-2-1-4(7(10)11)3-6(5)14(9,12)13/h1-3H,(H,10,11)(H2,9,12,13) |
| InChIKey | FHQAWINGVCDTTG-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=C(Cl)C(S(N)(=O)=O)=C1 |
| CAS DataBase Reference | 1205-30-7(CAS DataBase Reference) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| WGK Germany | 3 |
| RTECS | DG5642600 |
| HS Code | 29350090 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Toxicity | mouse,LD50,intravenous,> 2gm/kg (2000mg/kg),BEHAVIORAL: ATAXIABEHAVIORAL: TREMORLUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION,Kiso to Rinsho. Clinical Report. Vol. 16, Pg. 2275, 1982. |
4-Chloro-5-sulphamoylbenzoic acid Usage And Synthesis
| Chemical Properties | Off-White Solid |
| Uses | 4-Chloro-3-sulfamoylbenzoic Acid (cas# 1205-30-7) is a compound useful in organic synthesis. |
| Definition | ChEBI: 4-chloro-3-sulfamoylbenzoic acid is a sulfonamide. |
| General Description | 4-Chloro-3-sulfamoylbenzoic acid is the major metabolite of tripamide (N-(4-aza-endo-tricyclo[5.2.1.0(2,6))]-decan-4-yl)-4-chloro-3-sulfamoylbenzamide), new antihypertensive agent. It is present as impurity in clopamide tablets and has been quantitated by chromatographic-densitometric method. |
4-Chloro-5-sulphamoylbenzoic acid Preparation Products And Raw materials
| Raw materials | Benzoic acid, 3-(aminosulfonyl)-4-chloro-, methyl ester-->4-CHLORO-3-CHLOROSULFONYLBENZOIC ACID-->4-Chlorobenzoic acid |
