Introduction：Basic information about 4-Chlorobenzoyl chloride CAS 122-01-0, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
4-Chlorobenzoyl chloride Basic information
| Product Name: | 4-Chlorobenzoyl chloride |
| Synonyms: | LABOTEST-BB LTBB000569;4-Chlorobenzoyl chloride, 99+% 5ML;4-CHLOROBENZOYL CHLORIDE FOR SYNTHESIS;Chlorobenzene forMyl chloride;4-chloro-benzoylchlorid;Benzoyl chloride, 4-chloro-;Benzoyl chloride, p-chloro-;Benzoylchloride,4-chloro- |
| CAS: | 122-01-0 |
| MF: | C7H4Cl2O |
| MW: | 175.01 |
| EINECS: | 204-515-3 |
| Product Categories: | ACIDHALIDE;Absolute Configuration Determination (Exciton Chirality CD Method);Analytical Chemistry;Enantiomer Excess & Absolute Configuration Determination;Exciton Chirality CD Method (for Hydroxyl Groups);Acid Halides;Carbonyl Compounds;Organic Building Blocks;Absolute Configuration Determination;YP00036 |
| Mol File: | 122-01-0.mol |
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4-Chlorobenzoyl chloride Chemical Properties
| Melting point | 11-14 °C (lit.) |
| Boiling point | 102-104 °C/11 mmHg (lit.) |
| density | 1.365 g/mL at 20 °C (lit.) |
| vapor pressure | 5.8-73.9Pa at 20-50℃ |
| refractive index | n20/D 1.578(lit.) |
| Fp | 221 °F |
| storage temp. | Store below +30°C. |
| solubility | soluble in Chloroform, DMSO |
| form | Liquid |
| color | Clear colorless to faintly colored |
| explosive limit | 1.5-15%(V) |
| Water Solubility | Reacts with water. Reacts with alcohol. |
| FreezingPoint | 12~14℃ |
| Sensitive | Moisture Sensitive |
| BRN | 471606 |
| Stability: | Stable. Moisture sensitive. Incompatible with strong oxidizing agents. |
| InChI | 1S/C7H4Cl2O/c8-6-3-1-5(2-4-6)7(9)10/h1-4H |
| InChIKey | RKIDDEGICSMIJA-UHFFFAOYSA-N |
| SMILES | ClC(=O)c1ccc(Cl)cc1 |
| LogP | 2.52 at 25℃ |
| CAS DataBase Reference | 122-01-0(CAS DataBase Reference) |
| NIST Chemistry Reference | 4-Chlorobenzoic acid chloride(122-01-0) |
| EPA Substance Registry System | Benzoyl chloride, 4-chloro- (122-01-0) |
Safety Information
| Hazard Codes | C |
| Risk Statements | 34-36/37 |
| Safety Statements | 26-36/37/39-45-28A |
| RIDADR | UN 3265 8/PG 2 |
| WGK Germany | 1 |
| RTECS | DM6635510 |
| F | 10-19-21 |
| TSCA | TSCA listed |
| HazardClass | 8 |
| PackingGroup | II |
| HS Code | 29163900 |
| Storage Class | 8A - Combustible corrosive hazardous materials |
| Hazard Classifications | Aquatic Chronic 3
Eye Dam. 1
Skin Corr. 1B |
4-Chlorobenzoyl chloride Usage And Synthesis
| Uses | 4-Chlorobenzoyl Chloride is used as a promoter in the synthesis of α-aminonitriles. It is also used as a derivatization agent and self-assembling dipole molecule to improve hole injection in conjugated polymers. In addition. It is an important organic intermediate to synthetize substituted 4-chlorobenzoyl products. |
| Chemical Properties | liquid |
| Uses | 4-Chlorobenzoyl chloride was used to synthesize 4-chlorobenzoyl CoA by reacting it with CoA in KHCO3 buffer. 4-Chlorobenzoyl chloride may be used in the following studies Acylation of benzene using different solid acid catalysts such as dodecatungstophosphoric acid (DTPA), DTPA/K-10 clay, K-10, Amberlite, Amberlyst-15, Indion-130, Filtrol-24 clay and sulfated zirconia, Preparation of 1-(4-chlorobenzoyl)-2, 7-dimethoxynaphthalene, Preparation of 4-chlorobenzoyl CoA, via reaction with CoA in KHCO3 buffer, Preparation of 1-aryloxyacetyl-4-(4-chlorobenzoyl)-semicarbazides. |
| Definition | ChEBI: An acyl chloride consisting of benzoyl chloride having a chloro substituent in the para-position. |
| General Description | 4-Chlorobenzoyl chloride is an acyl chloride. It reacts with 2-amino-2-seleno-5,5-dimethyl-1,3,2-dioxaphosphorinane to yield the respective N-acyl selenophosphoramides. |
4-Chlorobenzoyl chloride Preparation Products And Raw materials
| Raw materials | Thionyl chloride-->4-Chlorobenzoic acid |
| Preparation Products | Moclobemide-->Rebamipide-->3-[2-chloro-2-(4-chlorophenyl)ethenyl]-2，2-dimethyl cyclopropane carboxylic acid-->4-chloro-1'-(4-methoxyphenyl)benzohydrazide-->Indometacin-->4-Chlorobenzophenone-->4-Chloro-4'-hydroxybenzophenone-->4-chloro-4'-methoxybenzophenone-->Fenofibrate-->4-Chloro-3',4'-dimethoxybenzophenone-->4,4'-Dichlorobenzophenone-->4-Chloro-alpha-methylstyrene-->Benzenecarbothioic acid, 4-chloro-, anhydrosulfide with thiocyanic acid-->2-chloro-4-(4-chlorophenyl)-6-phenyl-1,3,5-triazine-->4-CHLOROBENZOYLACETONITRILE-->4-CHLOROBENZOYL ISOTHIOCYANATE-->4-chloro-N-(7-oxo-7H-benzo[e]perimidin-6-yl)benzamide-->ethyl 4-({[(4-chlorobenzoyl)amino]carbonothioyl}amino)benzoate |
